| 血清CEA联合CA125，CYFR21—1，NSE检测在肺癌诊断中的临床评价 |
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| 引用本文： | 于海涛,刘秀娜.血清CEA联合CA125，CYFR21—1，NSE检测在肺癌诊断中的临床评价[J].山西临床医药,2014(1):26-28. |
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| 作者姓名： | 于海涛 刘秀娜 |
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| 作者单位： | 威海市文登中心医院,山东威海264400 |
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| 摘 要： | 目的：分析血清癌胚抗原（CEA）联合糖类抗原125（CA125）、细胞角蛋白19的可溶性片段（CYFRA21—1）、神经元特异性烯醇化酶（NSE）检测在肺癌诊断中的临床应用。方法：检测60例肺癌患者、30例正常体检者和30例肺部炎症患者的CEA，CA125，CYFRA21—1和NSE，对其进行对比分析。结果：四项肿瘤标志物CEA，CA125，CYFRA21—1，NSE在两组之间比较差异有统计学意义（P〈O．05）。结论：CEA，CA125，CYFRA21—1，NSE联合检测在肺癌诊断中具有临床使用价值。
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| 关 键 词： | 血清癌胚抗原 特异性烯醇化酶 联合检测 肺癌 |
The clinical evaluation on serum CEA,CA125,CYFR21--1,NSE for the diagnosis of lung cancer |
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| YU Hai-tao,LIU Xiu-na.The clinical evaluation on serum CEA,CA125,CYFR21--1,NSE for the diagnosis of lung cancer[J].Shanxi Clinical Medicine,2014(1):26-28. |
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| Authors: | YU Hai-tao LIU Xiu-na |
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| Institution: | (Wendeng Central Hospital of Weihai,Weihai 264400,China) |
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| Abstract: | Objective.. To analyze the clinical application of serum carcinoembryonic antigen （CEA）, carbohydrate antigen CA125, the soluble fragment of the joint cytokeratin 19 （CYFRA21-1） and neuron-specific enolase （NSE） to detect clinical application for the diagnosis of lung cancer. Methods;The serum CEA, CA125, CYFR21-1, NSE of 60 lung cancer cases, 30 normal healthy persons and 30 cases with inflammation of lung disease were detected and ana- lyzed. Results;The difference of four tumor markers, CEA, CA125, CYFRA21 - 1, NSE between the two groups was statistically significant （P〈0.05）. Conclusion;The joint detection of CEA,CA125, CYFRA21-1, NSE has clinical val- ue in the diagnosis of lung cancer. |
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| Keywords: | carcinoembryonic antigen neuron--specific enolase joint detection lung cancer |
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