| 血浆置换联合激素及免疫抑制剂治疗炎性肌病的临床研究 |
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| 引用本文： | 介绍亮,杨金华,闫成兰,赵文鹏,吴萌,丁丽娟,曹培龙,郝莉敏,陈俊伟. 血浆置换联合激素及免疫抑制剂治疗炎性肌病的临床研究[J]. 山西临床医药, 2014, 0(6): 406-409 |
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| 作者姓名： | 介绍亮 杨金华 闫成兰 赵文鹏 吴萌 丁丽娟 曹培龙 郝莉敏 陈俊伟 |
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| 作者单位： | [1]山西医科大学,山西太原030001 [2]山西医科大学第二医院,山西太原030001 |
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| 基金项目： | 本课题为山西医科大学第二医院新技术、新项目资助项目（项目编号201309）. |
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| 摘 要： | 目的：分析血浆置换联合激素及免疫抑制剂治疗炎性肌病的疗效。方法：总结并分析8例炎性肌病患者采用血浆置换联合激素及免疫抑制剂治疗和预后的情况。结果：8例血浆置换后四肢肌无力、面部皮疹等临床症状都有明显改善；8例血浆置换治疗后白细胞（WBC）、红细胞沉降率（ESR）、谷草转氨酶（AST）、肌酸激酶（CK）、肌酸激酶同工酶（CKMB）、乳酸脱氢酶（LDH）、羟丁酸脱氢酶（HBDH）较治疗前明显降低。结论：血浆置换联合激素及免疫抑制剂治疗炎性肌病疗效满意。
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| 关 键 词： | 特发性炎性肌病 血浆置换 糖皮质激素 免疫抑制剂 肌酶 |
The clinical study on plasmapheresis combined with glucocorticoid combined for inflammatory myositis |
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| Affiliation: | JIE Shao - liang , YANG Jin - hua, YAN Cheng - lan , ZHAO Wen - peng , WU Meng, DING Li - juan , CAO Pei - long , HAO Li - min, CHEN Jun - wei ( 1. Shanxi Medical University, Taiyuan 030001, China ;2. The Second Hospital of Shanxi Medical University, Taiyuan 030001, China) |
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| Abstract: | Objective：To investigate the effect of plasmapheresis combined with glucocorticoid combined for inflammatory myositis. Methods：To analyze the treatment and prognosis situation of plasmapheresis combined with glucocorticoid combined for 8 cases with inflammatory myositis. Results：The clinical symptoms of myasthenia and skin eruption have obvious improve-ment. The white blood cell（WBC）,erythrocyte sedmentation（ESR）,glutamic - oxaloacetic transaminase（AST）,creatine ki-nase（CK）,creatine kinase isoenzyme（CKMB）,lactate dehydrogenase（LDH）,hydroxybutyric dehydrogenase（HBDH）low-er than pretherapy. Conclsion：Plasmapheresis combined with glucocorticoid combined for inflammatory myositis has satisfactory curative effect. |
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| Keywords: | idiopathic inflammatory myositis plasmapheresis glucocorticoid immunosuppressant creatase |
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