绝经前合理应用维生素D和钙剂与绝经后妇女骨密度的关系

目的:调查绝经前后妇女的体成分与绝经年龄、身高及应用维生素D和钙剂后骨密度的关系。方法:采用1∶1配对设计方法,将196例妇女分为绝经期前未用维生素D和钙剂者和用维生素D和钙剂者两组,采用米尺和磅秤测量两组妇女的身高和体重,采用双能X线骨密度仪检测两组妇女的骨质疏松值,采用超声骨密度仪检测两组妇女的左侧跟骨的超声速度、骨硬度指数和低骨量。观察两族妇女体内骨密度指标。结果:绝经前后不同年龄组妇女体质指数、超声速度、骨硬度指数、低骨量及骨质疏松值比较差异有统计学意义(P<0.05)。应用维生素D和钙剂的妇女骨密度较未应用维生素D和钙剂的妇女同年龄组相比,骨质疏松值有所下降。结论:绝经前后妇女合理应用维生素D和钙剂安全、有效,可早期预防骨质疏松,值得推荐,特别适用于绝经后妇女。

Relationship between reasonable applications of vitamin D and calcium before menopause and bone mineral density of postmenopausal women

Objective:To investigate the relationship between body composition,menopausal age,body height and applications of vitamin D and calcium among the women before and after menopause.Methods:One hundred and ninety-six women were divided into treatment group and control group according to receiving vitamin D and calcium before menopause by 1∶ 1 matched pair technique;meter ruler and platform scale were used to measure the body height and body weight of the women in the two groups,dual-energy X-ray absorptiometry was used to detect osteoporosis values,ultrasonic bone density apparatus was used to measure the ultrasonic velocity,bone stiffness index,and low bone mass of the women in the two groups.Bone mineral densities of the women in the two groups were observed.Results:There was statistically significant difference in body mass index,ultrasonic velocity,bone stiffness index,and low bone mass among the women in different age groups before and after menopause(P>0.05);the osteoporosis value in treatment group was significantly lower than that in control group at the same age group.Conclusion:Vitamin D and calcium used reasonably are safe and effective for the postmenopausal women and premenopausal women,which can prevent osteoporosis,the method is worthy to be recommended and suitable for postmenopausal women.