液基细胞学联合人乳头瘤病毒检查在妊娠期宫颈病变筛查中的作用

目的:探讨液基细胞学(TCT)联合人乳头瘤病毒(HPV)检查在妊娠期宫颈病变筛查中的价值。方法:采用TCT联合HPV检查的方法,对在深圳市第二人民医院行产前检查的500例妊娠期妇女进行宫颈病变筛查,以宫颈组织病理学检查结果作为确诊的金标准。结果:500例中,高危HPV阳性检出率为28.00%,TCT阳性检出率为8.40%,HPV与TCT同时阳性与阴道镜活检病理结果的阳性符合率为89.29%。结论:产前检查是进行宫颈病变筛查的良好时机,TCT联合HPV检查与阴道镜活检病理结果的阳性符合率高,用于妊娠期宫颈病变筛查是安全和有效的。

Effect of liquid-based cytology combined with human papillomavirus test in screening of cervical lesions during pregnancy

Objective:To explore the value of liquid-based cytology combined with human papillomavirus(HPV) test in screening of cervical lesions during pregnancy.Methods:Liquid-based cytology combined with HPV test was used to carry out screening of cervical lesions in 500 pregnant women in the hospital,the pathological result of cervical tissue was designed as gold standard of definite diagnosis.Results:Among 500 pregnant women,the detection rate of high risk HPV was 28.00%,and the positive detection rate of liquid-based cytology was 8.40%,the positive coincidence rate between positive HPV test,liquid-based cytology and pathological result after colposcopic biopsy was 89.29%.Conclusion:Prenatal examination is a good opportunity for screening of cervical lesions;the positive coincidence rate between liquid-based cytology combined with HPV test and pathological result after colposcopic biopsy was high;the method is safe and effective for screening of cervical lesions during pregnancy.