| 不同程度的活血化瘀药对CCl_4慢肝模型的治疗作用 |
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| 引用本文： | 刘杰,陈斌.不同程度的活血化瘀药对CCl_4慢肝模型的治疗作用[J].中成药,1999(8). |
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| 作者姓名： | 刘杰 陈斌 |
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| 作者单位： | 湖南省中医药学校 |
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| 摘 要： | 通过动物实验观察不同程度活血化瘀药（和血药：当归、丹参；活血药：郁金、牛膝；破瘀药：莪术、虫）不同剂量（大剂量０．３２４ｇ／１００ｇ、小剂量０．０８１ｇ／１００ｇ）对大鼠ＣＣｌ４轻度慢肝模型的治疗作用。结果显示：和血药当归、丹参大剂量组和活血药郁金、牛膝小剂量组能显著提高ＳＯＤ活力，升高血清白蛋白含量，降低ＭＤＡ、ＡＬＴ。提示：活血化瘀药治疗慢肝损时，和血药剂量宜大，活血药剂量宜小，不宜选用破瘀药。
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| 关 键 词： | 活血化瘀药 抗慢性肝损伤 血清丙氨酸转氨酶（ALT） 血清白蛋白 超氧化物歧化酶（SOD） 丙二醛（MDA） |
Curative Effects of Different Degrees of Bloodquickening Stasisdispelling Medicinal on Chronic Hepatitis Model Induced by CCl4 |
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| LIU Jie,CHEN Bing.Curative Effects of Different Degrees of Bloodquickening Stasisdispelling Medicinal on Chronic Hepatitis Model Induced by CCl4[J].Chinese Traditional Patent Medicine,1999(8). |
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| Authors: | LIU Jie CHEN Bing |
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| Abstract: | The curative effects of bloodquickening stasisdispelling medicinal with different degrees(Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae; Radix curcumae, Radix Achyranthis Bidentatae; Rhizoma curcumae, Eupolyphaga seu Steleophaga) and different dosages(large dosage: 0.324g/100g and small dosage:0.081g/100g) for mildly chronic hepatitis model(rat) induced by CCl4 were investigated through the animal experiment. As a result, the large dosage group of Radix Angelicae Sinensis and Radix Salviae Miltiorrhizae and small dosage group of Radix curcumae and Radix Achyranthis Bidentatae could greatly increase the SOD activity and serumalbumin level, and decrease MDA and ALT. |
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| Keywords: | bloodquickening stasisdispelling medicinal antichronic liver damage ALT hyperseralbumin SOD MDA |
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