| CYFRA21-1、NSE和CEA在肺癌中的表达 |
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| 引用本文： | 施常备,付民,许建林,侯峥峰,贾晓娟,南永刚.CYFRA21-1、NSE和CEA在肺癌中的表达[J].现代肿瘤医学,2001,9(2):85-86. |
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| 作者姓名： | 施常备 付民 许建林 侯峥峰 贾晓娟 南永刚 |
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| 作者单位： | 陕西省肿瘤医院, |
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| 摘 要： | 目的分析CYFRA21－1、NSE和CEA在不同组织类型的肺癌中表达的差异。方法采用放免分析对13例正常人和37例肺癌患者进行血清CYFRA21-1、NSE和CEA的检测，统计分析各项指标在正常人、鳞癌、腺癌和小细胞肺癌患者之间的差别。结果CYFRA21-1在鳞癌、腺癌患者中表达水平较高，与小细胞肺癌及正常人有显著性差异；NSE在小细胞肺癌患者中表达水平较高，与鳞癌、腺癌及正常人有显著性差异；CEA在腺癌患者中表达水平较高，与鳞癌、小细胞肺癌及正常人有显著性差异。结论CYFRA21-1、NSE和CEA在肺癌中的表达与肺癌的组织类型密切相关。
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| 关 键 词： | CYFRA21-1 NSE CEA 肺癌 组织类型 |
| 文章编号： | 1008-7001(2001)02-0085-02 |
| 修稿时间： | 1999年12月8日 |
The expression of CYFRA21-1,NSE and CEA in lung carcinoma |
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| SHI Chang bei,FU Min,XU Jian lin,et al..The expression of CYFRA21-1,NSE and CEA in lung carcinoma[J].Journal of Modern Oncology,2001,9(2):85-86. |
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| Authors: | SHI Chang bei FU Min XU Jian lin |
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| Institution: | SHI Chang bei,FU Min,XU Jian lin,et al . Shaanxi Cancer Hospital,Xi'an 710061,China |
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| Abstract: | Objective To analyze the different expression of CYFRA21 1,NSE and CEA in varied histologic types of lung carcinoma.Methods Immunoradiometric assay and statistical analysis was used to study the levels of CYFRA21 1,NSE and CEA in the serum of 13 cases of normal persons, 37 cases of lung cancer patients.Results The CYFRA21 1 in squamous cell carcinoma or adenocarcionoma was higher than small cell lung cancer or normal persons and the difference was statistically significant. The NSE in small cell lung cancer was significantly higher than squamous cell carcinoma, adenocarcinoma or normal persons. The CEA in adenocarcinoma was significantly higher than squamous cell carcinoma, small cell lung cancer or normal persons.Conclusion The close relation between the quantity of CYFRA21 1,NSE and CEA in lung cancer and varied histologic types of lung carcinoma was seen. |
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| Keywords: | CYFRA21-1 NSE CEA lung cancer histologic type |
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