|
|||||
|
|
Risk factors for postoperative recurrence of non-B non-C hepatocellular carcinoma |
|
| Authors: | Hiroji Shinkawa Takahiro Uenishi Shigekazu Takemura Kazuki Ohba Masao Ogawa Tsuyoshi Ichikawa Shintaro Kodai Takatsugu Yamamoto Hiromu Tanaka Shoji Kubo |
| Affiliation: | 1. Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan 2. Department of Surgery, Ishikiri-Seiki Hospital, Higashi-Osaka, Osaka, Japan 3. Department of Surgery, Higashisumiyoshi Morimoto Hospital, Osaka, Japan |
| Abstract: | Background/purposeThe majority of hepatocellular carcinomas are associated with chronic infection with hepatitis B or C virus. Recently, however, the proportion of non-B non-C hepatocellular carcinomas has been increasing. It is necessary to determine the optimal surgical approach for non-B non-C hepatocellular carcinoma.MethodsSeventy-seven patients with non-B non-C hepatocellular carcinoma who underwent curative hepatic resection were included in this study. Univariate and multivariate analyses were performed to clarify risk factors for postoperative recurrence of non-B non-C hepatocellular carcinoma.ResultsOn univariate analysis, surgical margin <5?mm (P?=?0.001) and the presence of multiple tumors (P?=?0.002) were significantly associated with lower disease-free survival rate. On multivariate analysis, surgical margin <5?mm and the presence of multiple tumors were independent risk factors for postoperative recurrence.ConclusionCurative resection with adequate surgical margins for single non-B non-C hepatocellular carcinoma can achieve a good outcome. |
| Keywords: | non-B non-C HCC risk factor surgical margin |
| 本文献已被 SpringerLink 等数据库收录！ | |