脂质体经皮给药研究进展

目的：分析总结近年来国外脂质体经皮或黏膜给药研究的特点和应用进展。方法：对近年来脂质体药物特点，主要对在皮肤疾病和美容方面，对局部伤口的治疗，在皮肤损伤和保护中的应用，在眼科疾病中的应用进行综述。结果与结论：脂质体是一种很好的定向药物载体，它的应用将越来越广。

Advance in studies of liposome transdermal drug delivery system

OBJECTIVE:To summarize the advances of liposome transdermal drug delivery studies in recent years.METHOD:This technique provides a simple, clinically relevant approach to deliver therapeutic amounts of biogenic molecules to the skin, with potential application in treating a variety of cutaneous disorders and other diseases. These carriers can transport pharmacological agents, including large polypeptides, through the permeability barriers, such as the intact skin.RESULTS and CONCLUSION:Topically applied liposomes may be capable of targeting the delivery of a wide range of drugs, including macromolecules, into the body. Targeted drug delivery may have profound therapeutic applications for treating several diseases.