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大鼠离体心脏缺血再灌时冠脉流出液中肌钙蛋白T比较观察
引用本文:王建璞.大鼠离体心脏缺血再灌时冠脉流出液中肌钙蛋白T比较观察[J].心肺血管病杂志,1998,17(1):42-44.
作者姓名:王建璞
作者单位:河北省唐山市华北煤炭医学院附属医院麻醉科!100083(王建璞),北京医科大学第三临床医学院麻醉科!100083(王军,蒋建渝)
摘    要:在观察腺苷心脏停搏液的心肌保护效果时,应用酶联免疫吸附测定法对大鼠离休心脏冠脉流出液中的心脏肌钙蛋白T(TnT)进行检测,同时与心肌漏出酶(LDHCK)进行了检测比较。结果表明:1.TnT用于检测离体心脏心肌损伤程度可能比LDH和CK更敏感。2.TnT与LDH或CK相关性很好(r=0.901,r=0.869),LDH和CK相关性也很好(r=0.967)。

关 键 词:肌钙蛋白T  心肌损伤  离体鼠心

Comparison between Troponin T and Cardiac Enzymes in Coronary Effluent from Isolated Rat Hearts during Reperfusion
Wang Jianpu, Wang Jun, Jiang Jianyu..Comparison between Troponin T and Cardiac Enzymes in Coronary Effluent from Isolated Rat Hearts during Reperfusion[J].Journal of Cardiovascular and Pulmonary Diseases,1998,17(1):42-44.
Authors:Wang Jianpu  Wang Jun  Jiang Jianyu
Abstract:Troponin T(TnT) in coronary effluent from isolated rat hearts were detected using the enzyme-linked immuno-sorbent assay during the study of myocadial protective effects of adenosine cardioplegia. Cardiac enzymes(LDH, CK) levels were compared with that of TnT. These studies indicated that (1) the measurements of TnT might be more sensitive for the detection of myocardial damage in the isolated rat heaxts than that of LDH and CK and (2) there were strong correlation between TnT and LDH (r=0.901) or CK(r=0.869). Also, there was very close relationship between LDH and CK (r=0.967).
Keywords:Troponin T  Myocardial damage  Isolatad rat heart
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