| 乙型肝炎病毒DNA多聚酶活力的测定及其意义 |
| |
| 引用本文： | 李沛涛,胡国龄,张铮,甘晓明,余平.乙型肝炎病毒DNA多聚酶活力的测定及其意义[J].中南大学学报(医学版),1986(2). |
| |
| 作者姓名： | 李沛涛 胡国龄 张铮 甘晓明 余平 |
| |
| 作者单位： | 湖南医学院微生物学教研室
(李沛涛)，湖南医学院第一附属医院传染病科
(胡国龄，张铮，甘晓明)，湖南医学院微生物学教研室(余平) |
| |
| 摘 要： | 将陶氏免疫沉淀法加以变更,测定83例乙型肝炎(简称乙肝)病人及 50倒无症状HBsAg 携带者血清DNAP 活力,结果 DNAP活力增高的百分率是:急性乙型肝炎59.9,慢性活动性肝炎57.6,重症肝炎56.3,慢性迁延性肝炎 28.6,无症状携带者26.0。对一例携带者血清作免疫电镜观察,发现三种颗粒均存在。对HBeAg、抗-HBe 的产生与 DNAP活力增高的不一致性作了讨论。
|
| 关 键 词： | 乙型肝炎 带病原状态 乙型肝炎病毒 脱氧核糖核酸 聚合酶类 乙型肝炎e抗原 乙型肝炎表面抗原 免疫测定 |
DETECTION OF DNA POLYMERASE ACTIVITY OF HEPATITIS B VIRUS AND ITS CLINICAL SIGNIFICANCE |
| |
| Li Peitao.DETECTION OF DNA POLYMERASE ACTIVITY OF HEPATITIS B VIRUS AND ITS CLINICAL SIGNIFICANCE[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1986(2). |
| |
| Authors: | Li Peitao |
| |
| Institution: | Li PeitaoDepartment of Microbiology,Hunan Medical College Hu Guoling Zhang Zheng Gan XiaomingDepartment of Infectios Diseasens,The First Affiliated Hospital,Hunan Medical college |
| |
| Abstract: | Eighty-three cases of hepatitis B and 50 cases of asymptomatic HBsAg carriers were tested for DNA polymerase (DNAP) activity by modified Tao's immune precipitation technique. The rate of increase of DNAP activity was 59.9% in acute hepatitis, 57.6% in chronic active hepatitis, 56.3% in fulminant hepatitis, 28.6% in chronic persistent hepatitis, and 26% in asymptomatic carriers. The serum of an asymptomatic carrier was examined by immune electronmicroscopy, all three kinds of particles (Dane, small spherical, and tubular) were present. The inconsistency of HBeAg and anti-HBe positivity with DNAP activity is discussed. |
| |
| Keywords: | Hepatitis B Carrier state Hepatitis B virus DNA polymerases Hepatitis B e antigens Hepatitis B surface antigens Immuno-assay |
| 本文献已被 CNKI 等数据库收录！ |
|
