血尿酸水平与急性脑梗死相关性研究

①目的探讨血尿酸水平与急性脑梗死发病及预后的关系。②方法选取住院急性脑梗死患者94例为观察组,检测入院24小时内血尿酸水平及相关指标,并与正常对照组比较和分析两组间的相关性;分别对观察组病例入院第1天及第28天进行神经功能缺损评分,分析神经功能缺损与入院时血尿酸水平的相关性。③结果急性脑梗死患者血尿酸水平及异常率明显增高,与对照组之间存在显著差异(P<0.01);在急性脑梗死患者中,血尿酸异常组高血压、高脂血症、高纤维蛋白原血症及颈动脉粥样斑块的发生率较正常组明显增高(P<0.01),且前者入院第28天神经功能缺损的程度也较重(P<0.01)。④结论血尿酸水平与急性脑梗死的发病密切相关,参与了其发病机制,是预后不良的预测因素。

Correlation between the level of serum uric acid and acute cerebral infarction

Objective To study the correlation between the level of serum uric acid and the prognosis of acute cerebral infarction.Methods A total of 94patients with acute cerebral infarction were enrolled.Methods The level of serum wric acid and relative indexes in 24 hours in hospital were examined and the correlation was analysed between normal group and patient group The incompetent functions of the nerves of the patient group were valned on the lst day the 28th day in hospital,and the relation of the incompetent functions of the nerves and the level of serum uric acid was analysed.Results The level of serum uric acid and the abnormal rate of the acute cerebral infarction patients increased obviously and there were significant diferent coinpared with the wormal gronp(P<0.01);In the cerebral infarction patients,the incidences of hypertenstion,hyperlipidemia,hyperfibrinogenemia and atherosclerotic plaques incarotid arteries in the abnormal serum wric acid group increased obviously(P<0.01),and the degree of the incompetent functions of the nerves was much more serious on the 28th day in hospital(P<0.01).Conclustion The level of serum uric acid was a clos relation with acute cerebral infarction,and.was bad prognostic the predictable factor.