泌尿生殖道支原体感染862例及耐药性分析

目的研究泌尿生殖道支原体感染状况及对抗菌药物的耐药性。方法回顾性统计分析2008年10月—2009年10月862例泌尿生殖道分泌物样本支原体培养及药敏试验结果。结果 862例样本中,支原体培养阳性251例,阳性率为29.1%;其中解脲支原体(Uu)阳性219例,阳性率25.4%;人型支原体(Mh)阳性7例,阳性率0.8%;Uu和Mh混合阳性25例,阳性率2.9%;Uu对10种常用抗菌药物的药物敏感试验表明,耐药性较低的3种药物为美满霉素、强力霉素、克拉霉素;Uu+Mh混合感染对美满霉素、强力霉素、交沙霉素耐药率较低。结论泌尿生殖道支原体感染以Uu感染为主,在临床治疗中应合理使用抗生素,严格按照药敏试验结果合理用药以提高疗效,减少耐药菌株产生。

Urogenital Tract Mycoplasma Infection Its Resistance Analysis of 862 Cases

Objective]To study the mycoplasma infection in urogenital tract and its resistance to antibiotics.Methods]The Mycoplasma cultivation and the drug susceptibility test of urogenital tract secretions in 862 cases were retrospectively analyzed from October 2008 to October 2009.Results]Of 862 cases,251（29.1%） were infected with mycoplasma,219（25.4%） were infected with Uu.7（0.8%） were infected with Mh,.25（2.9%） were infected with Uu and Mh.By drug susceptibility test of Uu to 10 common antibacterial drugs,Uu had low resistance to minocycline,doxycycline,clarithromycin;Un ＋ Hh were sensitive to minocycline,doxycycline,josamycin.Conclusion]Uu is the main pathogen induces mycoplasma infection in urogenital tract.It＇s necessary to strengthen reasonable use of antibiotic in clinic,in strict accordance with the results of susceptibility testing,to improve efficacy and reduce the resistant strains.