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Cutaneous extramedullary hematopoiesis following splenectomy for idiopathic myelofibrosis
Authors:W G Hocking  G S Lazar  J A Lipsett  R W Busuttil
Affiliation:Los Angeles, California USA;Duarte, California USA;Los Angeles, California USA
Abstract:A 50-year-old man with idiopathic myelofibrosis had development of extensive cutaneous extramedullary hematopoiesis after undergoing splenectomy. Treatment with hydroxyurea was not effective, but electron-beam irradiation controlled the cutaneous infiltration. This rare clinical manifestation of idiopathic myelofibrosis can be confused with cellulitis, and diagnosis depends upon biopsy.
Keywords:Current address and address for reprint requests: Sections of Hematology and Oncology   Marshfield Clinic   1000 North Oak Avenue   Marshfield   Wisconsin 54449.
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