中西医结合治疗与单纯西医治疗失眠症疗效的Meta分析

目的:系统评价中西医结合与单纯西医药治疗失眠症的疗效.方法:计算机检索中国生物医学文献数据库、中国期刊网、万方数据库、维普数据库,并配合手工检索所有文献全文,由两位评价者分别对资料进行质量评价,用Revman 5.1进行Meta分析,主要对失眠的近期疗效进行分析.结果:共纳入13个随机对照试验,目前资料的Meta分析结果显示:临床治疗有效率:异质性分析df=12,P=0.007＜ 0.05,认为纳入文献不同质,故笔者采用随机模型,用比值比(OR)、95％的可信区间(CI)作为效应量的表达方式,结果提示合并效应量的OR为3.83,95％的可信区间为2.40 ～6.13,P＜0.000 01,差异有统计学意义,提示中西医结合治疗组优于单纯西药治疗组.结论:中西医结合治疗失眠症的疗效优于单纯西药治疗.

Meta-analysis of Integration of Traditional and Western Medicine Treatment Versus Western Treatment in Patients with Insomnia

Objective: To compare the effect of integration of traditional and western medicine with western medicine therapy for insomnia. Method: Relevant literatures were reviewed via database and assessed via randomized controlled trial (RCT) scale. All reviewed literatures were assessed via Jadad quality scale. Data statistical analysis were performed by RevMan 5.1 software. Result: Recently clinical efficient showed that since test for heterogeneity P=0.007<0.05, it indicates the data do not has homogeneity, so we use the random effect model. With OR=3.83, 95% CI, the effect size was between 2.40 and 6.13, P<0.000 01.It means that intergration of traditional and western medicine treatment for insomnia in improving clinical symptom has obvious advantages compared with western medicine. Conclusion: Integration treatment for insomnia shows curative effect, and there are obvious advantages compared with western medicine.