Oral methoxsalen photochemotherapy of recalcitrant dermatoses of the palms and soles |
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Authors: | WARWICK L. MORISON JOHN A. PARRISH THOMAS B. FITZPATRICK |
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Affiliation: | Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, U.S.A. |
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Abstract: | PUVA therapy successfully cleared various dermatoses mainly confined to the palms and soles in 18 of 20 patients treated. The conditions treated were: plaque-type psoriasis, pustular psoriasis, endogenous eczema and persistent palmoplantar pustulosis. Seventeen patients were treated in a controlled study of PUVA therapy versus no treatment at all and in 16 of these patients the disease was cleared in the PUVA-treated areas while the untreated areas remained unchanged or deteriorated. Twelve of the 18 patients were maintained in a clear state by continued maintenance PUVA treatment over 6–31 months while 3 patients had a spontaneous remission and are free of disease off all treatment. |
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