| 胸腔积液中肿瘤坏死因子和腺苷脱氨酶含量对结核性胸膜炎的诊断意义 |
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| 引用本文： | 关平,卢峰岳.胸腔积液中肿瘤坏死因子和腺苷脱氨酶含量对结核性胸膜炎的诊断意义[J].现代临床医学生物工程学杂志,1999(1). |
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| 作者姓名： | 关平 卢峰岳 |
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| 作者单位： | 广州市胸科医院!广州，510095，广州市胸科医院!广州，510095 |
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| 摘 要： | 目的：探讨肿瘤坏死因子（TNF）和腺苷脱氨酶（ADA）对结核性胸膜炎的诊断价值．方法：ADA采用比色法、TNF采用ELISA法对27例恶性胸腔积液、52例结核性胸腔积液进行检测．结果：结核性胸腔积液ADA和TNF水平都明显高于恶性胸腔积液，差别具有显著性（P＜0.01）．结论：应用TNF和ADA可能有助于结核性胸膜炎的鉴别诊断．
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| 关 键 词： | 肿瘤坏死因子（TNF） 腺苷脱氨酶（ADA） 结核 胸腔积液 |
Detection of TNF and ADA Levels in Pleural Effusion of Patients with Tuberculous Pleurisy |
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| Guan Ping, Lu Fengyue.Detection of TNF and ADA Levels in Pleural Effusion of Patients with Tuberculous Pleurisy[J].Journal of Modern Clinical Medical Bioengineering,1999(1). |
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| Authors: | Guan Ping Lu Fengyue |
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| Institution: | Guang Zhou Chest Hospital Guangzhou 510095 |
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| Abstract: | Objective: To investigate the diagnostic value of TNF and ADA levels in pleural effusions inpatients with tuberculous pleurisy. Method: The levels of ADA in the pleural effusion were determinedby colarimetric method, the levels of TNF were detemined by ELISA method, that included 52 casesof tubereulosis and 27 cases malignant pleural effusions, Results: The leveis of ADA and TNF weresignificantly higher in tuberculosis pleural effusions than that in malignant pleural effusions. There wassignificant difference of TNF and ADA levels in two groups (P<0.01). Conclusion: The determinationof TNF and ADA levels in pleural effusion may be useful in differential diagnosis of tuberculous andmalignent pleural effusions. |
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| Keywords: | Tumor necrosis factor(TNF) Adenosine deaminase(ADA) Tuberculousis Pleural effusion |
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