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良性前列腺增生术后前列腺癌
引用本文:华立新,张杰秀,吴宏飞,眭元庚,张炜,钱立新,王增军.良性前列腺增生术后前列腺癌[J].中华男科学杂志,2004,10(8):612-613.
作者姓名:华立新  张杰秀  吴宏飞  眭元庚  张炜  钱立新  王增军
作者单位:南京医科大学第一附属医院泌尿外科,江苏,南京,210029
摘    要:目的 :提高对前列腺增生术后前列腺癌的认识。 方法 :回顾总结 1 2例 (年龄 6 3~ 82岁 )前列腺增生术后前列腺癌患者的临床资料。前列腺增生术后 1 0个月~ 1 4年 ,平均 5 .6年 ,发现前列腺癌。患者因排尿困难、血尿、疼痛而再次就诊。发现前列腺特异抗原 (PSA)异常 1 1例 ,前列腺结节 8例。B期 3例、C期 3例、D期 6例。 1 2例均行睾丸切除术 ,其中 1 0例加用雄激素受体阻断剂 ,3例行经尿道前列腺切除术 (TURP)。 结果 :随访 4个月~ 8年 ,平均 4 .5年。死亡 3例 ,病变稳定 6例 ,2例病变进展。 结论 :前列腺增生手术不能预防前列腺癌的发生 ,血清PSA和直肠指检是前列腺增生术后前列腺癌诊断的主要方法

关 键 词:良性前列腺增生  前列腺癌
文章编号:1009-3591(2004)08-0612-02
修稿时间:2004年2月4日

Prostate Cancer after Prostatectomy for Benign Prostatic Hyperplasia
Hua Lixin,Zhang Jiexiu,Wu Hongfei,Sui Yuangeng,Zhang Wei,Qian Lixin,Wang Zengjun.Prostate Cancer after Prostatectomy for Benign Prostatic Hyperplasia[J].National Journal of Andrology,2004,10(8):612-613.
Authors:Hua Lixin  Zhang Jiexiu  Wu Hongfei  Sui Yuangeng  Zhang Wei  Qian Lixin  Wang Zengjun
Institution:Hua Lixin,Zhang Jiexiu,Wu Hongfei,Sui Yuangeng,Zhang Wei,Qian Lixin,Wang Zengjun Department of Urology,the First Affiliated Hospital,Nanjing Medical University,Nanjing,Jiangsu 210029,China
Abstract:Objective: To study the diagnosis and treatment of prostate cancer after prostatectomy for benign prostatic hyperplasia(BPH). Methods: Twelve cases of prostate cancer after prostatectomy for benign prostatic hyperplasia were reviewed and studied. The mean intervals between prostatectomy for BPH and the diagnosis of prostate cancer was 10 months to 14 years, 5.6 years on average . The main symptoms were dysuria,hematuria and pain.Serum prostate specific antigen (PSA) was elevated in 11 cases. Digital rectal examination (DRE) was abnormal in 8 cases. Three cases were in clinical stage B, 3 in stage C and 6 in stage D. Ten cases received combined androgen blockade therapy. Monotherapy with surgical castration was given to 2 cases. Three patients with urinary tract obstruction received additional treatment of TURP. Results: During the 4 months to 8 years follow up, 3 patients died, 6 remained stable and 2 deteriorated. Conclusion: Surgery for BPH could not prevent the development of prostate cancer. PSA and DRE were the main methods for the diagnosis of this prostate cancer.
Keywords:benign prostatic hyperplasia  prostate cancer
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