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Transient Acute Monoblastic Leukemia with Reciprocal (8; 16) (p11; p13) Translocation
Authors:L. Sainati   S. Bolcato  M. C. Cocito  L. Zanesco  C. Basso  A. Montaldi  A. L. Piovesan
Affiliation: a Department of Pediatrics, Padua University, Padua, Italyb Cytogenetics Unit, S. Bortolo Hospital, Vicenza, Italyc Neonatal Unit, Villa Salus, Mestre, VE, Italy
Abstract:The translocation of t(8;16)(p11;p13) has been demonstrated in the blasts of aphenotypically normal newborn baby with acute monoblastic leukemia. No antileukemic therapy was administered and spontaneous, complete remission was observed at 2 months of age. The patient remains well 18 months after the diagnosis and continues to have a normal hemogram.
Keywords:acute monoblastic leukemia  congenital  karyotype  spontaneous remission
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