情感语言语境联想刺激模式的fMRI研究

目的：建立功能核磁共振成像（functional Magnetic Resonance Image，fMRI）的语言情感刺激模式，探讨阅读联想具有正性情感（Positive Emotion）及负性情感（Negative Emotion）的语言时，大脑激活区域的差异。方法：健康志愿者6名，均为在校研究生．以汉语为母语，平而回波序列（Echo Planar Imaging，EPI），血氧水平依赖法（Blood Oxygenation Level—dependent MRI，BOLD）组块设计（Block Design）获取功能成像。嘱受试者注视具有正性或负性情感的二字中文词汇，理解其语义后进行联想。结果：受试者理解率和合作率为100％。受试者报告可以区分出两组任务代表不同的情感。一组产生兴奋、高兴的情绪，甚至想笑；而另一组产生悲伤、难过、不安的情绪。负性语育任务激活的区域较正性语言任务激活的区域广泛。负性任务趋向于双侧激活，主要激活了双侧额上回，额中回，中央前回，顶上小叶，颞上回，颞中回；正性语肓任务主要激活了左侧额上回，中央前回，顶上小叶，颞上回，颞下回及小脑。负性语言任务还见到扣带前回、杏仁体、丘脑、尾状核头及胼胝体的激活。正性语言任务及负性语青任务可见到枕叶的双侧激活。结论：情感的处理具有偏侧性。负性情感更易被诱发，并伴随更多的脑区被激活。枕叶可能参与情感处理。

Functional Magnetic Resonance Image Study on the Brain Areas Involved in Reading Emotion-positive and Emotion-negative Language

Objective: To explore the different brain areas activated by emotion-positive and emotion-negative word tasks,during the functional magnetic resonance image(fMRI) process.Methods: 6 healthy volunteers,with Han as their mother tongue,were required to think around the given words of either positive emotion or negative emotion.Functional images were collected by BOLD block design.Results: With 100% comprehension and cooperation,the subjects were able to tell two different emotions.The emotion-nagative words were prone to activate more areas than the positive ones,which involved superior frontal gyrus,superior temporal gyrus,superior parietal lobule on both hemisphere.The areas activated by emotion-positive words were mainly left hemisphere dominant.Conclusion: Negative emotion was easier to provoke and more areas were implicated in the process,which lay a basis for the research of patients with emotion and language disorders.