| 复方丹参注射液对门脉高压性胃病模型胃黏膜的保护作用及分子机制 |
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| 引用本文： | 孙元水,凌志强,许晓东,胡俊峰,钱振渊,赵仲生,施敦,叶再元. 复方丹参注射液对门脉高压性胃病模型胃黏膜的保护作用及分子机制[J]. 世界华人消化杂志, 2011, 0(21): 2269-2273 |
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| 作者姓名： | 孙元水 凌志强 许晓东 胡俊峰 钱振渊 赵仲生 施敦 叶再元 |
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| 作者单位： | 浙江省人民医院胃肠外科;浙江省肿瘤医院浙江省肿瘤研究所; |
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| 基金项目： | 浙江省中医药管理局科研基金资助项目,No.2006C045~~ |
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| 摘 要： | 目的:探讨复方丹参注射液对门脉高压性胃病(PHG)模型大鼠胃黏膜的保护作用及其分子机制,方法:采用一期部分门静脉缩窄法制备PHG大鼠模型,♂Wistar大鼠70只,随机分为3组:模型对照组(n=30）、复方丹参治疗组(n)=30)、正常对照组(n=10）.造模后各时段(5、10、15、20、30、45 d)处死大鼠取胃...
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| 关 键 词： | 复方丹参注射液 门脉高压性胃病 大鼠 |
Mechanism underlying the protective effect of Compound Danshen Injection against gastric mucosal lesion in rats with portal hypertensive gastropathy |
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| Abstract: | AIM: To explore the protective effect of Compound Danshen Injection against gastric mucosal lesion in rats with portal hypertensive gastropathy and to explore possible mechanism involved. METHODS: Portal hypertension was induced in Wistar rats by partial portal vein ligation. Sev-enty male rats were randomly divided into three groups: model control group (n=30), Compound Danshen Injection group (n=30) and normal control group (n=10). Rats were killed 5, 10, 15, 20, 30 and 45 days after model creation to obs... |
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| Keywords: | Compound Danshen Injection Portal hypertensive gastropathy Rat |
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