| 胰腺癌免疫治疗的研究现状 |
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| 引用本文： | 吴应冬,周国雄.胰腺癌免疫治疗的研究现状[J].世界华人消化杂志,2011(20):2091-2096. |
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| 作者姓名： | 吴应冬 周国雄 |
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| 作者单位： | 南通大学附属医院消化科; |
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| 基金项目： | 国家自然科学基金资助项目,No.81072028~~ |
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| 摘 要： | 胰腺癌是常见的恶性程度较高的消化系肿瘤之一,转移早、手术切除率低、放化疗效果差、死亡率极高.近年来对肿瘤免疫机制的研究有了很大的进展.人们对肿瘤抗原、免疫监视、免疫逃避、免疫耐受、T淋巴细胞信号转导、细胞因子以及抑制性树突状细胞(DCs)的调节、共刺激分子的下调、肿瘤微环境有了一定的认识,推动了胰腺癌免疫治疗的发展,并...
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| 关 键 词： | 胰腺癌 免疫治疗 现状 |
Recent advances in immunotherapy for human pancreatic cancer |
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| Ying-Dong Wu,Guo-Xiong Zhou.Recent advances in immunotherapy for human pancreatic cancer[J].World Chinese Journal of Digestology,2011(20):2091-2096. |
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| Authors: | Ying-Dong Wu Guo-Xiong Zhou |
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| Institution: | Ying-Dong Wu,Guo-Xiong Zhou,Department of Gastroenterology,the Affi liated Hospital of Nantong University,Nantong 226001,Jiangsu Province,China |
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| Abstract: | Pancreatic cancer is one of the common highly malignant digestive system tumors. It is associated with a high mortality rate because of early metastasis, low resection rate and poor chemoradiotherapy response. Advances in immunology, such as tumor antigen, immunological surveillance, immunological evasion, immunological tolerance, T cell signal transduction, regulation of cytokines and regulatory DCs, down-regulation of co-stimulatory molecules, and tumor microenvironment, have enriched our knowledge and pr... |
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| Keywords: | Pancreatic cancer Immunotherapy Recent advances |
| 本文献已被 CNKI 等数据库收录！ |
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