无症状性前列腺炎对精液参数的影响

目的:探讨无症状性前列腺炎对精液参数的影响。方法:对已诊断无症状前列腺炎的152例患者按EPS中的WBC水平进行分组:A组(WBC+～++)和B组(WBC+++～++++);并设立健康正常的个体作为对照组(C组)。检测指标包括:精液量、pH值、液化时间、精子浓度、精子存活率、a级精子百分率、正常形态精子百分率、WBC计数与相关的炎症细胞因子等。结果:精液参数中液化时间、a级精子百分率(%)和正常形态精子百分率(%):A组(24.5±5.2)min、(20.0±4.1)、(10.5±4.8)和B组(30.4±5.0)min、(10.0±3.8)、(7.5±4.2)与C组(18.5±5.3)min、(32.3±4.5)、(17.8±3.6)相比,以及B组与A组相比,差异均有显著性(P<0.001),而pH值、精液量、精子存活率、精子浓度:A组(7.6±0.3)、(3.0±1.1)ml、(56.0±6.0)%、(65.9±11.3)×106/ml,B组(7.7±0.3)、(2.8±1.2)ml、(52.3±6.3)%、(62.5±10.3)×106/ml和C组(7.5±0.2)、(2.9±1.2)ml、(62.1±5.3)%、(87.7±10.1)×106/ml差异均无显著性(P>0.05)。B组精液中IL-1β(58.64±30.82)pg/ml、TNF-α(50.57±27.48)pg/ml与C组IL-1β(17.68±5.65)pg/ml、TNF-α(23.50±4.80)pg/ml比较,显著上升(P<0.001)。结论:无症状性前列腺炎对精液主要参数有明显影响。

Impact of asymptomatic prostatitis on semen quality

Objectives：To study the impact of asymptomatic prostatitis on semen parameters.Method：Based on the count of WBC in EPS,we assigned 152 patients with asymptomatic（type IV） prostatitis to Groups A（WBC ＋ to ＋＋） and B（WBC ＋＋＋ to ＋＋＋＋）,and included 68 normal healthy men controls in Group C.All the patients were examined for the volume,pH value and liquefaction time of the semen,sperm concentration,sperm survival rate,grade a sperm percentage,morphologically normal sperm percentage,WBC count,and accompanying inflammatory cytokines.Results：The semen liquefaction time,grade a sperm percentage and morphologically normal sperm percentage were（24.5±5.2） min,20.0±4.1 and 10.5±4.8 in Group A,（30.4±5.0） min,10.0±3.8 and 7.5±4.2 in Group B,and（18.5±5.3） min,32.3±4.5 and 17.8±3.6 in Group C,with statistically significant differences between A and B（P0.01）.The pH value,semen volume,sperm survival rate and sperm concentration were 7.6±0.3,（3.0±1.1） ml,56.0±6.0 and（65.9±11.3）×106/ml in Group A,7.7±0.3,（2.8±1.2） ml,52.3±6.3 and（62.5±10.3）×106/ml in Group B,and 7.5±0.2,（2.9±1.2） ml,62.1.0±5.3 and（87.7±10.1）×106/ml in Group C,with no significant differences among the three groups（P0.05）.The contents of interleukin-1β（IL-1β） and tumor necrosis factor-α（TNF-α） in the semen were（58.64±30.82） pg/ml and（50.57±27.48） pg/ml in Group B,significantly increased as compared with（17.68±5.65） pg/ml and（23.50±4.80） pg/ml in Group C（P0.01） Conclusion：Asymptomatic prostatitis effects significant changes in the major parameters of the patient＇s semen quality.