| 吸烟对小鼠睾丸酶的影响 |
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| 引用本文： | 张静,张晨. 吸烟对小鼠睾丸酶的影响[J]. 地方病通报, 2006, 21(2): 8-10 |
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| 作者姓名： | 张静 张晨 |
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| 作者单位： | 新疆医科大学公共卫生学院,乌鲁木齐,830054;新疆医科大学公共卫生学院,乌鲁木齐,830054 |
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| 摘 要： | 目的观察吸烟对小鼠睾丸酶活性的影响,探讨吸烟致睾丸损伤的可能机制。方法用分光光度法检测睾丸组织匀浆中酸性磷酸酶(ACP)、乳酸脱氢酶(LDH)和一氧化氮合成酶(NOS)的活性。结果长时间吸烟可引起睾丸组织匀浆中酸性磷酸酶(ACP)、乳酸脱氢酶(LDH)的活性显著下降,一氧化氮合成酶(NOS)的活性显著升高。结论吸烟对睾丸中一些酶活性的影响可能是其引起雄性生殖损伤的机制之一。
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| 关 键 词： | 吸烟 睾丸 酸性磷酸酶 乳酸脱氢酶 一氧化氮合成酶 |
| 文章编号： | 1000-3711（2006）02-0008-03 |
| 收稿时间： | 2005-10-15 |
| 修稿时间： | 2005-10-152005-11-26 |
Effects of Smoking on Enzyme in Testis of Mice |
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| ZHANG Jing,ZHANG Chen. Effects of Smoking on Enzyme in Testis of Mice[J]. Endemic Diseases Bulletin, 2006, 21(2): 8-10 |
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| Authors: | ZHANG Jing ZHANG Chen |
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| Affiliation: | College of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830054, China |
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| Abstract: | Objective To study the effect of smoking on certain enzymes in the testis of mice and to explore the possible mechanism for reproductive damage in male mice by smoking.Methods Activities of acid phosphatase(ACP),lactate dehydrogenase(LDH) and nitric oxide synthase(NOS)in homogenate of the testis were determined with spectrophotometry.Results ACP and LDH of testis significantly decreased but activities of NOS increased after a long time smoking.Conclusions Effects of smoking on certain enzymes in the testis would be one of important mechanisms for reproductive damage. |
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| Keywords: | Smoking testis ACP LDH NOS |
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