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2型糖尿病的循证治疗
引用本文:王双.2型糖尿病的循证治疗[J].中国循证医学杂志,2004,4(5):346-350,354.
作者姓名:王双
作者单位:四川大学华西医院老年科,成都,610041
摘    要:以Meta-分析和随机对照试验文献为基础,回顾近年来用于2型糖尿病血糖控制的药物治疗及与衰老相关的糖尿病问题的循证证据.结果发现,胰岛素联合口服降糖药的治疗方案更能改善2型糖尿病患者的胰岛素抵抗和胰岛β细胞功能缺陷;应警惕老年2型糖尿病患者合并的认知功能障碍和抑郁症.

关 键 词:2型糖尿病  药物治疗  糖化血红蛋白  Meta-分析  随机对照试验  认知功能障碍  抑郁症
文章编号:1672-2531(2004)05-0346-06

Evidence-Based Treatment for Type 2 Diabetes Mellitus
WANG Shuang.Evidence-Based Treatment for Type 2 Diabetes Mellitus[J].Chinese Journal of Evidence-based Medicine,2004,4(5):346-350,354.
Authors:WANG Shuang
Institution:WANG Shuang.Department of Geriatrics,West China Hospital,Sichuan University,Chengdu 610041,China
Abstract:Based on literatures on Meta-analysis and randomized controlled trial, drug use and some geriatrics syndromes such as cognitive impairment and depression, in elderly diabetic patients were reviewed. Insulin plus oral hypoglycemic drugs was more rational therapy for insulin resistance and islet dysfunction in type 2 diabetes mellitus. We should pay more attention to cognitive impairment and depression in elderly type 2 diabetic patients.
Keywords:Type 2 diabetes mellitus  Pharmacological therapy  HbA1c  Meta-analysis  Randomized controlled trial  Cognitive impairment  Depression
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