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Studies on curcumin and curcuminoids. XXIII: Effects of curcumin on liposomal lipid peroxidation |
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| Authors: | Hanne Hjorth Tnnesen Gro Smistad Tove gren Jan Karlsen |
| Institution: | a Institute of Pharmacy, University of Oslo P.O. Box 1068, Blindem, 0316, Oslo 3, Norway b Biotechnology Centre of Oslo, University of Oslo P.O. Box 1125, Blindern, 0316, Oslo 3, Norway |
| Abstract: | The potential of curcumin as a photosensitzer, radical scavenger and iron-chelating agent within an artificial membrane (i.e., liposome) is discussed. Curcumin is found to have a dual effect on liposome stability, manifested as peroxidation of phospholipids in the membrane. Curcumin incorporated in the liposomes acts as a chelating agent of ferric and ferrous ions in the membrane. |
| Keywords: | Curcumin Radical scavenger Photosensitizer Chelating agent Liposomal lipid peroxidation |
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