| PSD-007加激光照射对小鼠H_(22)肝癌细胞琥珀酸脱氢酶的影响 |
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| 引用本文： | 耿明,刘健,刘彦仿. PSD-007加激光照射对小鼠H_(22)肝癌细胞琥珀酸脱氢酶的影响[J]. 医学争鸣, 1988, 0(2) |
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| 作者姓名： | 耿明 刘健 刘彦仿 |
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| 作者单位： | 济南军区总医院(耿明)，第四军医大学电镜室(刘健)，第四军医大学病理学教研室(刘彦仿) |
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| 摘 要： | 本文用定量电镜酶细胞化学方法,观察到小鼠H_(22)肝癌细胞经血卟啉衍生物PSD-007加激光照射后15、30、60min和2、6和24h后,线粒体琥珀酸脱氢酶活性逐渐下降。为探讨光动力学反应杀伤肿瘤细胞的机制提供了资料。
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| 关 键 词： | 血卟啉类 琥珀酸脱氢酶类 电子显微镜检查 组织细胞化学 酶抑制 激光 |
The Effect of PSD-007 and Laser on Mitochondrial Succinate Dehydrogenase of Mouse H22 Hepatoma Cells |
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| Geng Ming,et al.. The Effect of PSD-007 and Laser on Mitochondrial Succinate Dehydrogenase of Mouse H22 Hepatoma Cells[J]. Negative, 1988, 0(2) |
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| Authors: | Geng Ming et al. |
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| Affiliation: | Geng Ming,et al. Laboratory of Electron Microscopy |
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| Abstract: | With cytochemistry of enzyme's electron microscopy and texture analysis; system, the dynamic changes of mitochondrial SDH in mouse H22 hepatomas treated with PSD-007 and laser were observed. The reactivity and the numter of mitochondrial SDH decreased gradually from 15 minutes to 2 hours and competely lost up to 24 hours. |
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| Keywords: | hematoporphyrins succinate dehydrogenase electron microscopy cytochemistry enzyme repression lasers |
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