TORCH感染与不良妊娠关系的分析

目的比较正常妊娠和异常妊娠妇女血清TORCH感染情况。方法采用酶联免疫吸附试验（ELISA）对3851例妊娠（包括3449例正常妊娠和402例异常妊娠）妇女进行TORCH-IgM抗体检测。结果 3449例正常妊娠孕妇血清弓形虫（TOX）、风疹病毒（RUV）及巨细胞病毒（CMV）IgM抗体阳性率分别为0.32%、0.20%、1.88%,总阳性率为2.41%;402例异常妊娠妇女TOX、RUV、CMVIgM抗体阳性率分别为3.48%、2.74%、9.20%,总阳性率为15.42%。异常妊娠妇女TOX、RUV、CMV的IgM阳性率以及TORCH感染总阳性率明显高于正常妊娠孕妇,差异均有统计学意义（P〈0.05）。结论 TORCH感染与不良妊娠密切相关,应重视TORCH感染的早期筛查和诊治。

Analysis on the relationship between TORCH infection and abnormal pregnancy

Objective To compare TORCH infection between normal pregnancy and abnormal pregnancy in pregnant women.Method To detect the special TORCH-lgM antibody,serum samples from 3 851 pregnant women（3 449 with normal pregnancy and 402 with abnormal pregnancy included） were tested by the method of enzyme linked immunosorbent assay（ELISA）.Results The positive rates of TOX-IgM,RUV-IgM and CMV-IgM in the serum of normal pregnant women were 0.32%,0.20%,and 1.88%,respectively,with a total positive rate of 2.41%.The positive rates of TOX-IgM,RUV-IgM and CMV-IgM in the serum of abnormal pregnant women were 3.48%,2.74%,9.20%,respectively,with a total positive rate of 15.42%.The positive rates of TOX-IgM,RUV-IgM and CMV-IgM in normal pregnancy group were significantly lower than those in abnormal pregnancy group（P〈0.05）.Conclusion TORCH infection was closely related to abnormal pregnancy,and early screening,diagnosis and treatment for TORCH infection should be performed in pregnant women.