| 乙拉西坦的合成 |
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| 引用本文： | 卢传广,王洪刚,王洪锋. 乙拉西坦的合成[J]. 齐鲁药事, 2005, 24(8): 484-485 |
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| 作者姓名： | 卢传广 王洪刚 王洪锋 |
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| 作者单位： | 鲁南制药集团股份有限公司,临沂,276005 |
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| 摘 要： | 目的合成乙拉西坦。方法2-吡咯烷酮经N-烷基化、氨解反应合成乙拉西坦。结果及结论总收率50·7%,乙拉西坦结构经1H-NMR,13C-NMR和IR确证。
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| 关 键 词： | 乙拉西坦 吡咯烷酮 合成 |
| 文章编号： | 1672-7738(2005)08-0484-02 |
Synthesis of Etiracetam |
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| Lu Chuan-guang,Wang Hong-gang,WANG Hong-feng. Synthesis of Etiracetam[J]. qilu pharmaceutical affairs, 2005, 24(8): 484-485 |
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| Authors: | Lu Chuan-guang Wang Hong-gang WANG Hong-feng |
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| Abstract: | Objective To synthesize Etiracetam. Methods Etiracetam was synthesized from 2-pyrrolidone by N-alkylation and aminolysis. Results and conclusion The overall yield was 50.7 % and the structure of Etiracetam was characterized by ^1H- NMR,^13C-NMR and IR. |
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| Keywords: | Etiraeetam pyrrolidone synthesis |
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