降逆和胃汤治疗非糜烂性反流病80例临床观察

目的：观察降逆和胃汤治疗非糜烂性反流病的临床疗效。方法：160例符合纳入标准的非糜烂性反流病患者，随机分为2组。治疗组80例，口服降逆和胃汤，每天1剂；对照组80例，口服雷贝拉唑钠肠溶胶囊10mg，每天2次；疗程均为8周。结果：应用降逆和胃汤和雷贝拉唑钠肠溶胶囊治疗非糜烂性反流病，均能明显改善患者的临床症状，治疗组总有效率为93．75％；对照组总有效率为80．00％；2组治疗后各症状积分均明显低于治疗前（P〈0．01），而治疗后治疗组病人的临床症状（如烧心、反酸、胸骨后疼痛、反食症状）与对照组比较有明显改善（P〈0．05）。结果显示，应用降逆和胃汤治疗非糜烂性反流病，能明显改善患者的烧心、反酸、胸骨后疼痛及反食等临床症状，且近期疗效和停药3月后复发情况都明显优于雷贝拉唑钠肠溶胶囊（P〈0．05）。结论：降逆和胃汤对非糜烂性反流病具有较好的疗效。

Clinical Observation on Jiangni Hewei Decoction in Treatment of Nonerosive Reflux Disease

Objective:To investigate the therapeutic effect of Jiangni Hewei Decoction on nonerosive reflux disease(NERD).Methods:One hundred and sixty qualified NERD patients were equally randomized into the treatment group(n=80) and the control group(n=80).The treatment group was treated with Jiangni Hewei Decoction orally,one dose per day.The control group was given rabeprazole,10mg twice per day.The course of treatment lasted 8 weeks.Results:The total effective rate was 93.75% in the treatment group and 80.0% in th...