| 市售保泰松片溶出度方法的考察 |
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| 引用本文： | 姜泽慧,吴勇. 市售保泰松片溶出度方法的考察[J]. 中国药师, 2014, 0(6): 962-964 |
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| 作者姓名： | 姜泽慧 吴勇 |
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| 作者单位： | 马鞍山市食品药品检验所 安徽马鞍山243000;马鞍山市食品药品检验所 安徽马鞍山243000 |
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| 基金项目： | 安徽省科研课题（编号：.10021303018） |
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| 摘 要： | 目的：建立保泰松片溶出度的检测方法.方法：从溶出方式、溶出介质、转速3个因素考察,紫外分光光度法测定,对不同厂家批次的保泰松片的溶出曲线进行对比研究.结果：采用桨法,以pH6.8磷酸盐缓冲液为溶出介质,转速为100 r·min-1,考察市售保泰松片的溶出度.结论：此方法准确、可靠,可用于评价保泰松片的质量.
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| 关 键 词： | 保泰松片 溶出度 质量评价 |
| 收稿时间： | 2013-12-30 |
| 修稿时间： | 2014-03-15 |
Study on Dissolution of Marketed Phenylbutazone Tablets |
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| Jiang Zehui and Wu Yong. Study on Dissolution of Marketed Phenylbutazone Tablets[J]. China Pharmacist, 2014, 0(6): 962-964 |
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| Authors: | Jiang Zehui and Wu Yong |
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| Affiliation: | Maanshan Institute for Food and Drug Control, Anhui Maanshan 243000, China;Maanshan Institute for Food and Drug Control, Anhui Maanshan 243000, China |
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| Abstract: | Objective：To establish a method for the dissolution determination of phenylbutazone tablets.Methods：Comparison of dissolution curves for different batches of phenylbutazone tablets was presented by UV spectrophotometry with three factors,including the dissolution mode,medium and speed.Results：The dissolution determination conditions of phenylbutazone tablets were as follows：an oar method was used with the stiring speed of 100 r · min-1,and the dissolution medium was pH 6.8 phosphate buffer.Conclusion：The method is accurate and reliable,and can be used to evaluate the quality of phenylbutazone tablets. |
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| Keywords: | Phenylbutazone tablets Dissolution Quality evaluation |
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