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补肾活血法对EMs大鼠模型细胞因子的影响
引用本文:周艳艳. 补肾活血法对EMs大鼠模型细胞因子的影响[J]. 河南中医药学刊, 2008, 0(1): 35-36
作者姓名:周艳艳
作者单位:河南省中医院,河南郑州450002
基金项目:感谢褚玉霞教授对本文的指导
摘    要:方法:用补肾活血中药调经助孕胶囊混悬液灌胃于六组大鼠(模型空白组、丹那唑对照组、调经助孕胶囊高、低剂量组、空白对照组及假手术组),对大鼠细胞因子(TNF—α、IL-2、IL-8、)进行观察。目的:探讨调经助孕胶囊的作用机制,进而为EMs的临床治疗提供依据。结果:模型组大鼠的TNF—α、IL-2、IL-8同模型空白组相比均升高,调经助孕胶囊组大鼠与模型组大鼠的TNF—α、IL-2、IL-8相比显著降低。结论:EMs确有细胞因子含量的升高,调经助孕胶囊能降低TNF—α、IL-2、IL-8来治疗EMs。

关 键 词:二紫胶囊  子宫内膜异位症  细胞因子  实验研究  大鼠

The Effect of Invigorate the Kidney and Promoting Blood Flow on Cytokine of Eros Rats Model
Zhou Yanyan. The Effect of Invigorate the Kidney and Promoting Blood Flow on Cytokine of Eros Rats Model[J]. Journal of Henan college of Traditional Chinese Medicine, 2008, 0(1): 35-36
Authors:Zhou Yanyan
Affiliation:Zhou Yanyan(Henan Province Hospital of Chinese Medicine, Zhengzhou, Henan, China, 450002)
Abstract:Objective: to approach the mechanism of action of regualting menstruation to help fetation capsule to provide the evidence for clinic. Method: the rats were divided 6 groups as follow: control, model, danazol, high and lower regualting menstruation to help fetation capsule and sham operation and the TNF-α, IL - 2 and IL - 8 were observed. Results: the TNF - α, IL - 2 and IL - 8 were in model higher than control and lower than regualting menstruation to help fetation capsule. Conclusion: the cytokine content was high in endometriosis and the regualting menstruation to help fetation capsule had the function to degrade the TNF-α、IL- 2 and IL - 8 to treat endornetriosis.
Keywords:Erzi capsule  endometriosis  cytokine  empirical study  rat
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