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Genome‐wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences
Authors:Meghan J Chenoweth  Jennifer J Ware  Andy Z X Zhu  Christopher B Cole  Lisa Sanderson Cox  Nikki Nollen  Jasjit S Ahluwalia  Neal L Benowitz  Robert A Schnoll  Larry W Hawk Jr  Paul M Cinciripini  Tony P George  Caryn Lerman  Joanne Knight  Rachel F Tyndale
Institution:1. Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada;2. Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada;3. MRC Integrative Epidemiology Unit (IEU) and School of Social and Community Medicine, University of Bristol, Bristol, UK;4. Data Science Institute and Lancaster University Medical School, Lancaster, UK;5. Department of Preventive Medicine and Public Health, University of Kansas School of Medicine, Kansas City, KS, USA;6. Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA;7. Departments of Medicine and Bioengineering and Therapeutic Sciences, Division of Clinical Pharmacology and Experimental Therapeutics, University of California, San Francisco, CA, USA;8. Department of Psychiatry, Perelman School of Medicine, and Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA;9. Department of Psychology, University at Buffalo, SUNY, Buffalo, NY, USA;10. Department of Behavioral Science, University of Texas, MD Anderson Cancer Center, Houston, TX, USA;11. Division of Schizophrenia, Centre for Addiction and Mental Health, Toronto, ON, Canada;12. Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Toronto, ON, Canada;13. Department of Psychiatry, Annenberg School for Communication, and Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA;14. Department of Psychiatry, University of Toronto, Toronto, ON, Canada
Abstract:
Keywords:African Americans  cigarette smoking  CYP2A6  genome‐wide association study  nicotine metabolism biomarker  treatment‐seeking smokers
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