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Mood disorders and prospective suicidality in young adults: a population‐based cohort study
Authors:D. C. Vieira  T. de Azevedo Cardoso  T. C. Mondin  K. Jansen  R. A. da Silva  L. D. de Mattos Souza  F. Kapczinski  P. V. S. Magalhães
Affiliation:1. Post Graduate Program in Psychiatry and Behavioral Sciences, Federal University of Rio Grande do Sul (UFRGS), RS, Brazil;2. Post‐Graduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas, RS, Brazil;3. Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada
Abstract:

Objective

To assess the prospective associations of mood disorders and suicidality in a community sample of young adults from south Brazil.

Method

Prospective population‐based cohort study. Young adults (18–24 years old) were recruited and followed up on 5 years later; people were interviewed at their homes. Suicidality, as well as mood and anxiety disorders, was assessed using the Mini‐International Neuropsychiatric Interview. The impact of mood episodes on suicidality was both evaluated when they occurred in the same wave (a current episode) and when suicidality occurred prospectively, with suicidality measured at follow‐up (a past episode).

Results

The sample included 1560 young adults at baseline, with 1244 reassessed at follow‐up (80.6%). Depressive episodes, both current and past, had a significant impact on suicidality in the final multivariable model. Manic episodes, however, were less consistently associated with suicidality.

Conclusion

Depressive episodes have a strong, independent, and robust association with prospective suicidality. The association between manic episodes and suicidality, on the other hand, was dependent on the analysis and deserves further exploration.
Keywords:suicide  mood disorders  community sample  longitudinal study
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