首页 | 本学科首页   官方微博 | 高级检索  
     

国产与进口西替利嗪片治疗常年性变应性鼻炎的比较
引用本文:张官萍,李永奇,王继群,卢迪卿. 国产与进口西替利嗪片治疗常年性变应性鼻炎的比较[J]. 中国新药与临床杂志, 1999, 18(6): 359-360
作者姓名:张官萍  李永奇  王继群  卢迪卿
作者单位:1. 中山医科大学第三临床学院耳鼻咽喉科,广东广州510630
2. 暨南大学医学院附属医院耳鼻喉科,广东广州510632
3. 广州医学院第二附属医院变态反应科,广东广州510260
摘    要:目的:比较国产与进口西替利嗪片对常年性变应性鼻炎的疗效及不良反应。方法:常年性变应性鼻炎203 例,国产组111 例( 男性59 例,女性52例,年龄36 a ±s 7 a) ,进口组92 例( 男性52 例,女性40 例,年龄39 a±9 a) , 分别给予国产与进口西替利嗪片10 mg , po ,qd,7 d 为一个疗程,共1 ~2个疗程。结果:有效率国产组为86 % ,进口组为87 % ( P> 0 .05) , 显效时间分别为2 .5 d ±1 .3 d 及2 .4 d ±1 .2 d( P> 0 .05) ; 不良反应发生率国产组为18 % ,进口组为15 % ,( P> 0 .05) 。结论:国产西替利嗪片在治疗常年性变应性鼻炎的疗效及不良反应与进口西替利嗪片相近。

关 键 词:西替利嗪  常年性变应性鼻炎  鼻疾病

Domestic vs imported cetirizine tablets in treating perennial allergic rhinitis
ZHANG Guan-Ping,LI Yong-Qi,WANG Ji-Qun,LU Di-Qing. Domestic vs imported cetirizine tablets in treating perennial allergic rhinitis[J]. Chinese Journal of New Drugs and Clinical Remedies, 1999, 18(6): 359-360
Authors:ZHANG Guan-Ping  LI Yong-Qi  WANG Ji-Qun  LU Di-Qing
Abstract:AIM: To compare the efficacy and adverse reaction of domestic and imported cetirizine tablets in treating perennial allergic rhinitis (PAR). METHODS: Two hundred and three PAR patients were divided into 2 groups at random. Domestic group of 111 patients (M 59, F 52; age 36 a±s 7 a) and imported group of 92 patients (M 52, F 40; age 39 a±9 a) took domestic and impoted cetirizine tablets (10 mg, po, qd, 7 d a course, 1_2 courses), respectively. RESULTS: The improvements of duration of symptoms and physical signs in 2 groups were similar (P>0.05). The total clinical effective rate of domestic group is 86%, and the imported group 87%(P>0.05). The rate of adverse reaction in domestic group is 18%, and imported gorup 15%(P>0.05). CONCLUSION: The clinical efficacy and adverse reaction of domestic cetirizine tablets are similar to that of the imported cetirizine in the treatment of PAR.
Keywords:cetirizine  perennial allergic rhinitis  nose diseases
本文献已被 CNKI 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号