心血通治疗高血压性头痛疗效优于脉络宁

目的：比较心血通与脉络宁治疗高血压性头痛的疗效。方法：１３１ 例住院高血压性头痛病人，随机分为２ 组，心血通组６８ 例（ 男性３７ 例，女性３１例；年龄６３ ．４ ａ ±ｓ １ ．９ ａ） ，经常规降压药物治疗头痛不减轻而加用心血通１０ ｍ Ｌ／ｄ ，静脉滴注（ 静滴）×１４ ｄ ； 脉络宁组６３ 例（ 男性３３ 例，女性３０ 例；年龄６１ ．５ ａ ±２ ．１ ａ） 用脉络宁２０ ｍ Ｌ／ｄ ，静滴×１４ ｄ 。结果：心血通组临床总有效率为８７ ％ ，优于脉 络宁组的５２ ％ （ Ｐ ＜ ０ ．０５） ；治疗后心血通与脉络宁组 Ｑｍ ｅａｎ 左右和 Ｖｍ ｅａｎ 左右均显著增加（ Ｐ＜ ０ ．０１） ， Ｒｖ左右均显著下降（ Ｐ＜ ０ ．０１） ，但组间比较心血通组效果更明显（ Ｐ＜ ０ ．０１） ；２ 组均无不良反应。结论：心血通治疗高血压性头痛效果较脉络宁好，且安全。

Xinxuetong is better than Mailuoning in treating hypertensive headache

AIM: To compare the efficacies of Xinxuetong and Mailuoning in treatment of hypertensive headache. METHODS: Sixty_eight patients(M 37, F 31 ; age 63.4 a±s 1.9 a) with hypertensive headache were given Xinxuetong 10 mL and the other similar 63 patients (M 33, F 30; age 61.5 a±2.1 a) were given Mailuoning 20 mL iv drip qd for 14 d in addition to conventional therapy. RESULTS: The total symptomatic effective rates were 87% in the former group and 52 % in the latter group (P<0.05). On the left and right the increases in Q mean and V mean and the decreases in R v (P<0.01) were found in both the groups after treatment, but in the former group above targets changes are more remarkable than those in the latter group (P<0.01). CONCLUSION: Xinxuetong is a better effective and safe drug than Mailuoning in the treatment of hypertensive headache.