脑卒中先兆证候分类与血压、血脂、血液流变学的相关性研究

目的：探讨脑卒中先兆证候分类的客观指标。方法：对84例脑卒中先兆病人按中医证候分组，观察各组病人血压、血脂、血液流变学变化，并与相同例数的正常对照组相比较。结果：肝胆火旺、痰瘀闭阻证组血压明显高于风痰内盛、瘀血阻络证组及气阻两虚、脉络瘀滞证组（P＜0．05）；肝胆火旺、痰瘀闭阻证组、风痰风盛、瘀血阻络证组及气阴两虚、脉络瘀滞证组脂质变化均较正常对照组明显升高（P＜0．05－0．01）；其中肝胆火旺、痰瘀闭阻证组及风痰内盛、瘀血阻络证组与气阴两虚、脉络瘀滞证组比较有统计学意义（P＜0．05）；三证型组血液流变学指标较正常组有统计学意义（P＜0．05－0．01）。结论：血压、血脂、血液流变学改变可为脑卒中先兆证候分类提供客观指标。

Study of Relationships Between the Different Syndromes and the Blood Pressure,Blood-Liqid,Blood Rheological in Patients with Premonition Symptoms of Apoplexy

Objective:To explore the objective criterion of the premonition symptom of apoplexy.Methods:84 cases premonition symptom of apoplexy were divided into 3 groups according to the TCM differentiation. Blood pressure,blood-liqid and blood rheological changes were investigated in each group.Results:The blood pressure level in hyperactivity of fire of liver and gallbladder & obstruction of collaterals by phlegm were much higher than the blood stasis and hyperactivity of wind-phlegm & obstruction of collaterals by blood stasis and deficiency of both Qi and Yin & collaterals stagnant. Comparied with the normal group,the blood-lipid dramatically rised in the group of hyperactivity of fire of liver and gallbladder & obstruction of collaterals by phlegm and blood stasis and hyperactivity of wind-phlegm & obstruction of collaterals by blood stasis and deficiency of both Qi and Yin & collaterals stagnant. There was remarkable different between hyperactivity of fire of liver and gallbladder & obstruction of collaterals by phlegm ,blood stasis and hyperactivity of wind-phlegm & obstruction of collaterals by blood stasis and deficiency of both Qi and Yin & collaterals stagnant. The level of blood rheological changed dramatically in 3 groups compared with the normal group.Conclusion: Blood pressure,blood-liqid and blood rheological changes may provide criterion for the premonition symptom of apoplexy differentiation.