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展望分子谱系地理学在道地药材研究中的应用
引用本文:袁庆军,黄璐琦,郭兰萍,邵爱娟. 展望分子谱系地理学在道地药材研究中的应用[J]. 中国中药杂志, 2009, 34(16): 2007-2011
作者姓名:袁庆军  黄璐琦  郭兰萍  邵爱娟
作者单位:中国中医科学院,中药研究所,北京,100700
基金项目:国家重点基础研究发展计划(973)项目(2006CB504700)
摘    要:作者在介绍分子谱系地理学的概念、研究方法和研究现状的基础上,探讨了分子谱系地理学推断的3种植物遗传分化模式--异域片断化、受距离影响的有限基因流和分布区快速扩展与道地性形成的相关性;阐述了基于分子谱系地理学研究的道地药材分子鉴定对以往分子鉴定局限的突破;阐明了分子谱系地理学在道地药材产地变迁历史研究中的应用;论述了分子谱系地理学在解决道地药材栽培中种质退化问题等方面的作用.这些方面的应用展现了分子谱系地理学在道地药材研究中的应用前景,为道地药材的研究提供了新的理论和方法.

关 键 词:道地药材  分子谱系地理学  遗传分化  分子鉴定  产地变迁  种质退化
收稿时间:2008-12-05

Prospect of application of molecular phylogeography in study of geoherbs
YUAN Qingjun,HUANG Luqi,GUO Lanping and SHAO Aijuan. Prospect of application of molecular phylogeography in study of geoherbs[J]. China Journal of Chinese Materia Medica, 2009, 34(16): 2007-2011
Authors:YUAN Qingjun  HUANG Luqi  GUO Lanping  SHAO Aijuan
Abstract:This paper firstly introduces the concept, method and current research of molecular phylogeography and then discusses its application in the study of geoherbs. The relativity between three genetic differentiation patterns of plant inferred by molecular phylogeography (i. e. allopatric fragmentation, restricted gene flow with isolation by distance and range expansion) and the formation of genuine character is analysed. Molecular authentication of geoherbs based on molecular phylogeography has the advantage of former molecular identification at technology and knowing genetic differentiation of geoherbs. Using molecular phylogeography for study on changing history of geoherbs habitat is also explicated. The problem of germplasm degeneration in cultural geoherbs could be effectively resolved by molecular phylogeography method. The application of molecular phylogeography in these subjects opens up prospects for study on geoherbs by using the principle and method of molecular phylogeography.
Keywords:geoherbs   molecular phylogeography   genetic differentiation   molecular authentication   geoherbs habitat change   germplasm degeneration
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