腹腔镜和开腹手术对早期胃癌术后近期生活质量的对比分析

目的对比分析早期胃癌治疗中经腹腔镜治疗与开腹手术治疗对患者生活质量的影响。方法随机将2011年3月至2015年5月130例拟接受手术治疗的早期胃癌患者分为两组,每组65例。开腹组接受开腹手术治疗,腹腔镜组接受腹腔镜手术治疗。对比两组手术相关情况及术前及术后1个月后的生活质量变化情况。以SPSS 19.0进行统计分析,手术时间、进食时间、下床时间、术中出血量及FACT-G-V4评分均以均数±标准差进行描述,t检验分析;术后并发症发生率以卡方检验。P0.05为具有统计学差异。结果腹腔镜组手术时间、进食时间及下床时间分别为(91.56±56.26)min、(4.29±1.21)d及(4.29±1.21)d均明显短于开腹组的(121.36±63.26)min、(6.36±1.16)d及(17.12±5.21)d(t=2.837,P=0.003;t=9.956,P=0.000;t=4.287,P=0.000),腹腔镜组术中出血量为(115.89±36.66)ml明显少于开腹组(211.61±49.36)ml(t=12.552,P=0.008);术后总并发症发生率开腹组为13.85%(9/65),腹腔镜组为3.07%(2/65),腹腔镜组明显低于开腹组,差异均有统计学意义(χ2=4.303,P=0.038)。结论与传统手术比较经腹腔镜手术治疗可显著的改善早期胃癌患者术后的生活质量。

Comparative study of short-term life quality of patients with early gastric cancer underwent open or laparoscopic gastrectomy

Objective To compare the short-term life quality of patients with early gastric cancer underwent open or laparoscopic gastrectomy. Methods From March 2011 to May 2015, 130 patients with early gastric cancer were randomly divided into two groups, 65 cases in each group.Patients in open group received open operation, while laparoscopic surgery were performed in laparoscopy group .Clinical data of patients and their perioperative 1 month changes of life quality were observed and compared in two groups.Statistical analysis were performed by using SPSS 19.0 software.Measurement data were expressed as mean ±SD and were examined by t test, including operation time, recovery time of taking food, ambulation time, intraoperative blood loss and FACT-G-V4 scoring.Complications were compared by chi-square test.P less than 0.05 was considered as significant difference. Results In laparoscopy group, operation time of (91.56 ±56.26) min, recovery time of taking food of (4.29 ±1.21) d, ambulation time of (4.29 ±1.21) d were significantly decreased than (121.36 ± 63.26) min, (6.36 ±1.16) d, and (17.12 ±5.21) d in open group respectively (t=2.837, P=0.003;t=9.956, P=0.000, t =4.287, P=0.000).Moreover, intraoperative blood loss of (115.89 ±36.66) ml in laparoscopy group was significantly less than (211.61 ±49.36) ml in open group (t=12.552, P=0.008). Postoperative complication rate of 3.07%(2/65) in laparoscopy group was lower than 13.85%(9/65) in open group, with significant difference (χ2=4.303, P=0.038). Conclusion Compared with traditional operation, Laparoscopic surgery could significantly improve postoperative quality of life of patients with early gastric cancer .