液基薄层细胞学检测法在宫颈癌筛查中的应用

目的对液基薄层细胞检测系统（ThinPrep cytology Test，TCT）及巴氏系统（the Behesda system，TBS）细胞学分类法在宫颈癌筛查中的应用价值进行综合评价。方法采用液基薄层细胞检测系统检测宫颈细胞并进行TBS细胞学分类诊断，将诊断意义不明确的不典型鳞状细胞（ASCUS）以上病变均列为阳性病例，且在阴道镜下行活检，将细胞学检测结果与活检结果作对比分析。结果液基薄层细胞学检测法标本满意率99％，1002例涂片中阳性病例106例，阳性率4．22％。对76例异常者行阴道镜下活检与组织病理学诊断总符合率81．5％（62／76）。结论TCT技术应用宫颈细胞涂片筛查，明显提高了涂片的满意率及宫颈异常细胞检出率。TBS报告方式内容直观、易懂、具体。TCT检查异常的病例配合阴道镜病理检查进行最后诊断。能及早发现宫内早期病变，是防治宫颈癌发生的关键。

APPLICATION OF LIQUID BASED CYTOLOGY TEST AND BEHESDA SYSTEM CYTOLOGY SUBDIVISION IN CERVICAL CANCER

Objective To study the value of Thinprep cytology Test (TCT) and the Behesda system(TBS) cytology subdision in cervix cancer. Methods 1800 cases were detected by TCT and TBS. The samples of atypical squamoha cell and more abnormal cell were positive, then compared the positive results with colposcopical biopsy examination. Results The satisfactory rate of TCT smears was 95%,76 samples were positive, the positive rate was 4.33%.Of these 76 cases,62 cases were agreement with the pathological examination, the rate of agreement was 81.5%(62/76). Conclusion If combined colpiscopical with pharmological examination, TCT could find out the early cervix lesion as soon as possible. The TBS cytology subdivision is more detailed, simple and direct. It is the key to prophylaxs and treat cervix cancer.