| 急性心肌梗塞患者血浆内皮素水平变化的意义 |
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| 引用本文： | 刘芳,孙述强.急性心肌梗塞患者血浆内皮素水平变化的意义[J].河北医药,1997,19(3):129-130. |
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| 作者姓名： | 刘芳 孙述强 |
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| 作者单位： | 河北医科大学第三医院内三科
050051(刘芳，王士昌，王矞辉)，河北医科大学第三医院同位素科
050051(孙述强)，河北医科大学第三医院同位素科 050051(刘晓梅) |
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| 摘 要： | 动态观察２８例急性心肌梗塞患者血浆内皮素及血清肌红蛋白水平的变化，并同时选择１３例不稳定心绞痛患者和１５例健康人做对对照。结果表明、ＡＭＩ组血中ＥＴ及Ｍｂ水平平均于梗塞２４小时之内达峰值，且随病程延长而逐渐下降，７天后降至正常范围；ＡＭＩ组血浆ＥＴ水平显著高于ＵＡ组及正常组，其中ＵＡ组又明显高于正常组；
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| 关 键 词： | 心肌梗塞 内皮素 肌红蛋白 心绞痛 |
Significance of Changes of Plasma Endothlin Levels in the Patiens with Acute Myocardial Infarction |
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| Liu Fang,et al.Significance of Changes of Plasma Endothlin Levels in the Patiens with Acute Myocardial Infarction[J].Hebei Medical Journal,1997,19(3):129-130. |
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| Authors: | Liu Fang |
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| Abstract: | The levels of plasma endothelin (ET) and serum myoglobin (Mb)of 28 patients with acute myocardial infarction (AMI) were monitored, meantime 13 unstable angina (UA) pa-tients and 15 healthy people (normal group) were selected as the controls. The results showed: the peak of circulating ET and Mb arrived within 24 hours after AMI, the levels of ET and Mb fell gradually and restored to normal one 7 days after AMI. The levels of plasma ET in group AMI were higher markedly than that of group UA and normal group (P<0. 01), and the levels of plas-ma ET of group UA were higher than normal group (P<0. 01). Correlative analysis between in-crease of plasma ET and serum Mb in group AMI was positive (r=0. 5832,P<0. 01). The above results prompted that detemine of plasma ET levels in AMI could act as a parameter to monitor the clinical course and estimate the degree of myocardium injury. |
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| Keywords: | Myocardial infarction Endothelin Myoglobin Angina |
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