老年女性冠心病相关因素分析

目的探讨老年女性冠心病患者患病相关因素分析。方法选择临床诊断为可疑冠心病的老年女性患者139例,根据冠状动脉造影结果分为冠心病组(71例)和对照组(68例),观察年龄、体重、吸烟、停经时间、血尿酸水平、血压、血脂、糖尿病、骨质疏松与冠心病的相关性,进一步分析其相关的危险因素。结果冠心病组与对照组在肥胖、吸烟、过早停经、血尿酸增高、高血压、高脂血症、糖尿病、骨质疏松方面差异有统计学意义(P0.01);年龄在2组间的分布差异无统计学意义(P0.05)。老年女性冠心病的危险因素是糖尿病和骨质疏松。结论冠心病是一种多因素疾病,对于老年女性而言,糖尿病、骨质疏松可能是其发病的危险因素;吸烟、高血压、高脂血症、过早停经、肥胖、血尿酸增高等因素可能与其发病有关。

Cardiovascular risk factors in elderly women patients with coronary artery disease

Objective To analyze the correlative factors of atherosclerosis in elderly women patients (≥60 years of age) with coronary artery disease and to study the possible cardiovascular risk factors. Methods 139 elderly women patients with suspected coronary artery disease were studied and divided into two groups based on the result of coronary angiography:coronary artery disease group (n = 71) and control group (n = 68).Comparisons were made between the two groups concerning nine factors:age,obesity,smoking,premature menopause,blood uric acid,hypertension, hyperlipemia,diabetes and osteoporosis.The possible risk factors for the prevalence of coronary artery disease were identified.Results The differences of eight factors,including obesity,smoking, premature menopause,blood uric acid,hypertension,hyperlipemia,diabetes and osteoporosis, between coronary artery disease group and control group were statistically significant (P < 0.01) ,but difference of age was not significant (P> 0.05).The risk factors for coronary artery disease in elderly women patients were diabetes and osteoporosis.Conclusions Coronary artery disease is a multifactorial disease of elderly women.Diabetes and osteoporosis may be the important risk factors for coronary artery disease in elderly women patients,while smoking,hypertension, hyperlipemia,premature menopause,obesity and increased serum uric acid may be related to its pathogenesis.