钠及超滤曲线透析模式对透析时低血压的影响

目的 探讨钠及超滤曲线模式对透析低血压的作用,以及对透析中血钠浓度的影响.方法 选择10例较常发生透析低血压的维持性血液透析患者,每例进行标准血液透析模式和钠及超滤曲线透析模式治疗5次,分别观察两种模式下患者的血压、心率、超滤量及症状发生率变化,并观察患者的血钠浓度变化.结果 钠及超滤曲线透析模式较标准血液透析模式低血压发生率明显下降(P＜0.01),超滤量前者较后者明显增加(P＜0.01),两组透析后血钠浓度无明显变化(P＞0.05).结论 钠及超滤曲线透析模式明显降低了透析患者低血压发生率,提高了透析患者的耐受性,并未增加患者的钠负荷,是一种安全、行之有效的透析模式.

Application of sodium profile combined with ultrafiltration profile in preventing intradialytic hypotension

Objective To study the efficacy of sodium profile combined with ultrafiltration profile in preventing intradialytic hypotension and changes of the sodium level in blood plasma after hemodialysis. Methods 10 patients with maintenance hemodialysis were chosen randomly. Every patient underwent with conventional hemodialysis treatment and sodium profile combined with ultrafiltration profile treatment 5 times alternatively. And then the blood pressure changes. HR changes, ultrafiltration volume changes and clinical symptoms were observed during treatments. And also after HD, the sodium level in blood plasma was observed. Results The blood pressure decrease of sodium profile combined with ultrafiltration profile evidently reduced the conventional HD treatments( P＜0.01 ).Ultrafiltration volume of the former evidently increased compared with that of the latter(P＜0.01 ). The sodium level in blood plasma after HD was not significantly changed compared with before HD(P＞0.05). Conclnsion Sodium profile combined with ultrafiltration profile diminishes the episodes of hypotension evidently and increases the ability to endure sufferirgs to patients and does not increase the sodium level in blood plasma. So it is an effective medical treatment.