不规则肝切除加肝动脉置泵治疗肝癌疗效分析

目的评价不规则肝切除加肝动脉置泵化疗对肝癌术后复发率及生存率的影响.方法对比分析近15年来66例肝癌患者单纯肝切除(48例)与肝切除加肝动脉置泵化疗(18例)的临床资料.结果单纯手术组与手术联合化疗泵组1、3、5年术后复发率分别为66.7%对38.9%、85.4%对55.6%、93.8%对72.2%,差异有显著性(P＜0.05).两组病人1、3、5年生存率分别为58.3%对88.9%、41.7%对72.2%、12.5%对38.9%,差异有显著性(P＜0.05).结论肝癌不规则肝切除加肝动脉置泵化疗可明显降低术后复发率、提高生存率.

A study on the effect of irregular hepatectomy combined with placing pump insidehepatic artery for the treatment of hepatic cancer

Objective To evaluate the effects of irregular hepatectomy combined with chemotherapy by placing pump inside hepatic artery on the postoperative recurrence rate and the postoperative survival rate. Methods The clinical data of 66 cases of hepatic cancer treated in the last 15 years were reviewed. 48 cases out of 66 cases were treated with simple hepatectomy and 18 cases with hepatectomy combined with chemotherapy by placing pump inside hepatic artery. Results There was a significant diference in the 1 year or 3 years or 5 years recurrence rate which were 66.7% to 38.9%, 85.4% to 55.6%, 93.8% to 72.2%, respectively in simple hepatectomy group and operation-chemotherapy group ( P <0.05). In this two groups, there was a significant difference in the 1 year or 3 years or 5 years postoperative survival rate which were 58.3% to 88.9%, 41.7% to 72.2%, 12.5% to 38.9%, respectively. ( P <0.05) Conclusion Irregular hepatectomy combined with chemotherapy by placing pump inside hepatic artery can decrease the postoperative recurrence rate and improve the postoperative survival rate in treatment of hepatic cancer.