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棘形红细胞尿对糖尿病肾病与非糖尿病肾病鉴别诊断的临床意义研究
引用本文:衣利,包继键,舒贵扬,林棱,姚瑾.棘形红细胞尿对糖尿病肾病与非糖尿病肾病鉴别诊断的临床意义研究[J].福建医药杂志,2012,34(4):24-25.
作者姓名:衣利  包继键  舒贵扬  林棱  姚瑾
作者单位:衣利 (福建医科大学省立临床学院综合内科,福州,350001) ; 包继键 (福建省汀州医院内三科) ; 舒贵扬 (福建省汀州医院本院肾内科) ; 林棱 (福建医科大学省立临床学院综合内科,福州,350001) ; 姚瑾 (福建医科大学省立临床学院综合内科,福州,350001) ;
摘    要:目的探讨棘形红细胞尿对糖尿病肾病(DN)与非糖尿病肾病(NDRD)鉴别诊断的临床意义以期指导临床。方法对在我科及肾内科住院诊治的22例合并有血尿的DN患者与33例合并有血尿的NDRD患者的尿棘形红细胞进行相差显微镜观察计数,并进行对比研究;所有病例均行肾穿刺活检术提供病理学依据。结果 NDRD组及DN组的棘形红细胞尿的检出率分别为:69.5%和4.5%,两者相比具有统计学意义。结论合并血尿的DM患者出现肾功能损害时,若发现棘形红细胞尿则考虑可能合并NDRD,需要尽快行肾穿刺活检术以明确其病理类型,以便指导临床治疗。

关 键 词:棘形红细胞尿  糖尿病肾病  非糖尿病肾病

Clinical value of acanthocyturia in differential diagnosis of diabetic nephropathy and nondiabetic renal disease
YI Li,BAO Ji-jian,SHU Gui-yang,Lin Leng,YAO Jin.Clinical value of acanthocyturia in differential diagnosis of diabetic nephropathy and nondiabetic renal disease[J].Fujian Medical Journal,2012,34(4):24-25.
Authors:YI Li  BAO Ji-jian  SHU Gui-yang  Lin Leng  YAO Jin
Institution:.Department of integrative interal medicine,Provincial Clinical Medical College institute of Fujian Medical University,Fuzhou,Fujian 350001,China
Abstract:Objective To investigate the clinical value of acanthocyturia in differential diagnosis of diabetic nephropathy(DN) and nondiabetic renal disease(NDRD).Methods Acanthocytes in urine of twenty patients of DN and thirty patients of glomerulonephritis with hematuria were observed and compared.All the patients had been given renal biopsy.Results Acanthocyturia was found in 76.7% of patients with glomerulonephritis,in 5.0% of patients with DN(P<0.001).Conclusion The finding of acanthocyturia in patients of DN with hematuria points to nondiabetic glomerulopathies,and renal biopsy should be considered.
Keywords:acanthocyturia  diabetic nephropathy  nondiabetic renal disease
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