Portland Cement用于根尖屏障材料的封闭性研究

目的通过离体实验观察波特兰水门汀(Portland Cement,PC)作为根尖屏障的封闭性,并将其与无机三氧化物聚合物(mineral trioxide aggregate,MTA)、玻璃离子水门汀(glass ionomer cement,GIC)、银汞合金(amalgam,Am)作比较。方法选取单根前磨牙64颗,行根管预备并制备根尖开放模型。完全随机分组法将实验用离体牙分为A、B、C、D 4个实验组,根尖部分别充以PC、MTA、GIC、Am,每组15个样本,阴性对照组及阳性对照组每组各2个样本。使用4%牛血清白蛋白作为观测指标连续观测60 d,用考马斯亮蓝染色技术对蛋白渗出做定量测定。结果 A组与B组蛋白渗出量无明显统计学差异,A组与C、D组蛋白渗出量比较有统计学差异(P<0.05),B组与C、D组蛋白渗出量比较有统计学差异(P<0.05)。随着时间的延长,A组蛋白渗出量的增加无统计学意义。结论 PC的根尖封闭性与MTA相当,且明显优于GIC、Am。

Sealing ability of Portland Cement as apical barrier: an in vitro study

Objective To study the sealing ability of Portland Cement(PC) as apical barrier in vitro,and to compare the sealing ability of PC with that of mineral trioxide aggregate(MTA),glass ionomer cement(GIC) and amalgam(Am).Methods Sixty-four premolars with single root canal were instrumented and set as open root apex modle.The premolars were randomly divided into an experimental group and a control group.The experimental group were subdivided into group A,group B,group C and group D(n=15),and each group of teeth were filled with PC,MTA,GIC and Am,respectively.The control group was subdivided into a negative control group and a positive control group(n=2).Coomassie brilliant blue was applied for quantitative determination of protein leakage using 4% bovine serum albumin for continuous 60 d.Results The protein leakage between group A and group B had no significant statistically difference(P>0.05).The protein leakage of group A showed significant statistically difference when compared with that of group C and D(P<0.05),and the same results were found in group B compared with group C and group D(P<0.05).The increase of protein leakage with time in the group A showed no significant statistically difference(P>0.05).Conclusion Sealing ability of PC is better than that of GIC and Am,and is the same as that of MTA when used as apical barrier filling materials.