急、慢性支气管炎患者血清TH的水平分析

目的：为了研究TH（甲状腺激素）与急、慢性支气管炎患者病情严重程度的关系。方法：本文利用RIA和CLIA测定了107例急性支气管炎,87例慢性支气管炎治疗前后和47例正常对照组血清中的FT3,T3,FT4,T4,TSH和T3/rT3的水平。结果：47例正常对照组血清FT3,T3,FT4,T4,TSH和T3/rT3的水平分别为（4.81±1.31）pmol/L,（1.34±0.41）ng/ml,（14.61±3.33）pmol/L,（84.11±18.70）ng/ml,（2.46±1.39）mIu/L和2.61±0.67,男女之间无明显差异（P〉0.05）。107例急性支气管炎、87例慢性支气管炎治疗前后血清FT3,FT4,T4和TSH水平与正常对照组无明显差异（P〉0.05）;而血清T3明显降低（P〈0.05或〈0.01）,rT3明显增高（P〈0.05或〈0.01）;慢性支气管炎治疗后较治疗前血清T3明显增加（P〈0.05）,血清rT3明显降低（P〈0.05）。结论：本文表明,急慢性支气管炎患者血清中T3和T3/rT3水平是重要的标志物,并能反映疾病的严重程度。

Study on the Serum Thyroid Hormones Levels in Patients with Acute and Chronic Bronchitis

Objective To study the changes of serum thyroid hormones levels in patients with acute bronchitis and chronic bronchitis.Methods Serum T3,FT3,T4,FT4,TSH(with CLIA) and rT3(with RIA) levels were measured in 107 patients with acute bronchitis,87 patients with chronic brouchitis and 47 controls.Results The serum thyroid hormones levels in all these patients were not significantly different from those in controls(P>0.05),except that the serum T3 levels were significantly lower and rT3 levels significantly higher(P<0.05 or P<0.01).The serum T3 levels increased significantly and rT3 levels decreased significantly after treatment(P<0.05).Conclusion Serum T3 levels could reflect the severity of the disease,the T3/rT3 ratio was lowest in the 10 deceased patients.