| 不同配液方式对安灭菌输液剂中微粒变化的影响 |
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| 引用本文： | 闫红丽,张金立,李月,柴雅静,沈丹,谢宇.不同配液方式对安灭菌输液剂中微粒变化的影响[J].河北职工医学院学报,2011(2):62-65. |
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| 作者姓名： | 闫红丽 张金立 李月 柴雅静 沈丹 谢宇 |
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| 作者单位： | 河北大学附属医院;保定市急救中心; |
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| 摘 要： | 目的了解不同溶媒、不同溶药方法及不同放置时间对粉剂抗生素类药物阿莫西林克拉维酸钾（安灭菌）溶解配伍后不溶性微粒的污染情况。方法将安灭菌（规格1.2g,30支）随机分为3组,每组10支。1组用0.9%氯化钠注射液（NS）10mL溶安灭菌1支,加入规格为100mL的NS中;2组用自带溶媒10mL溶安灭菌1支,加入规格为100mL的NS中;3组用自带溶媒10mL溶安灭菌1支后,用WzR-D951A型药用电子振荡器摇匀,充分溶解后加入规格为100mL的NS中。配伍后于5、30、60、120min时测定液体中不同直径的不溶性微粒数。结果安灭菌配伍后不溶性微粒变化与溶剂选择、溶药方法和放置时间有关。结论配伍安灭菌最好选择自带溶媒并应用药物振荡器使之充分溶解,配伍后的溶液在5～60min为给药最佳时间。针对此问题提出护理对策,可提高输液安全性。
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| 关 键 词： | 粉剂抗生素 安灭菌 配液方式 不溶性微粒 |
The influence of different dissolving methods on particulate matter in Amoxicillin intravenous infusion |
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| YAN Hongli,ZHANg Jinli,Li Yue,CHAi Yajing,SHeN Dan,Xie Yu.The influence of different dissolving methods on particulate matter in Amoxicillin intravenous infusion[J].Journal of Hebei Medical College for Continuing Education,2011(2):62-65. |
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| Authors: | YAN Hongli ZHANg Jinli Li Yue CHAi Yajing SHeN Dan Xie Yu |
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| Institution: | YAN Hongli1,ZHANg Jinli2,Li Yue1,CHAi Yajing1,SHeN Dan1,Xie Yu1(1.Affiliated Hospital of Hebei University,Baoding 071000,China,2.The First Aid Center of Baoding,China) |
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| Abstract: | Objective To study powder antibiotics amoxicillin clavulanate potassium dissolved application compatibility of different solvents,electronic oscillators and different place time of particulate matter pollution.Methods 30 branches of amoxicillin,specifications 1.2g,were randomly divided into 3 groups,10 branches in each group.The first group of 0.9% sodium chloride injection suction(NS) 10mL solution sterilized a safety specification was added in 100mL NS;the second group with their own security solution of ... |
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| Keywords: | antibiotic powder Amoxicillin dissolving methods particulate matter |
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