Secondary sclerosing cholangitis: an experimental study |
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| Authors: | G Pappalardo F M Frattaroli A Ioppolo E Conti D Reggio G Di Macco G Castrini |
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| Affiliation: | Second Surgical Clinic, University of Rome La Sapienza, Medical School, Italy. |
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| Abstract: | An experimental study on rabbit sclerosing cholangitis (SC) secondary to direct injection into the biliary tract of the chemical substances commonly employed for intraoperative sterilization of the hydatid cyst content is reported. Among the various substances utilized, 10% formalin and 30% hypertonic solution caused gross and microscopic lesions compatible with less advanced forms of sclerosing cholangitis. The authors present their hypothesis on the development of SC in operated hydatid cysts of the liver. |
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