甲状旁腺功能减退症患者血清心肌酶与血钙和心电图的动态分析

选择甲状旁腺功能减退症患者24例,正常对照24名,测定所有入选对象的血清心肌酶谱和血清总钙浓度,并对甲状旁腺功能减退症组进行心电监测.甲状旁腺功能减退症组患者血清肌酸磷酸激酶(CK)、肌酸磷酸激酶同工酶(CK-MB)、α-羟丁酸脱氢酶(BHDH)、乳氢脱氢酶(LDH)、天冬氨酸转氨酶(AST)均较对照组升高(均P＜0.05),以CK、CK-MB升高为明显(P＜0.01),酶学异常患者心电图均提示不同程度的心肌缺血.治疗后,随血钙浓度升高,心肌酶及心电图均于8周左右基本恢复正常.提示了血清心肌酶水平的变化可作为甲状旁腺功能减退症患者病情程度及治疗效果判定的参考指标.

Dynamic analysis of myocardial enzymes, serum calcium, and electrocardiogram in patients with hypoparathyrodism

24 cases of hypoparathyroidism, 24 cases of normal control were included. The levels of enzymes, concentration of Ca were measured in all cases. The electrocardiogram was carried out in the hypoparathyroidism group carries. The levels of CK, CK-MB, BHDH, LDH and AST were significantly higher in patients with hypoparathyroidism than in normal control cases(P＜0.05), especially the levels of CK and CK-MB (P＜0.01). After the treatment, the electrocardiogram and enzymes basically returned to normal. The changes of enzymes in patients with hypoparathyroidism may play a benchmark about the severity and treatment.