| 电针足三里穴对兔单肺通气所致氧化应激反应的影响 |
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| 引用本文： | 任秋生,陈雪琴,王均炉,包峰峰,蒋柳明. 电针足三里穴对兔单肺通气所致氧化应激反应的影响[J]. 中华中医药学刊, 2011, 0(12): 2738-2740 |
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| 作者姓名： | 任秋生 陈雪琴 王均炉 包峰峰 蒋柳明 |
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| 作者单位： | 宁波市鄞州人民医院;温州医学院第一附属医院; |
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| 基金项目： | 宁波市医学科技计划项目(2008029) |
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| 摘 要： | 目的:观察电针足三里对兔单肺通气期间氧化应激途径及肺损伤程度的影响。方法:健康成年新西兰兔39只,随机分为3组(n=13):电针非穴位组(EN组)、电针穴位组(EP组)、对照组(C组)。麻醉后气管切开,插入气管导管,双肺通气30min后,行右肺单肺通气,3 h后重新恢复双肺通气。EN、EP两组于单肺通气开始时实施电针刺激,EN组取双侧足三里穴旁1cm处,EP组取双侧足三里穴处。实验结束后处死动物,测定肺组织丙二醛(MDA)、谷胱甘肽过氧化酶(GSH-PX)和超氧化物歧化酶(SOD)含量,观察肺组织病理形态学,计算肺组织湿/干重比(W/D)。结果:EP组与其他两组比较,MDA明显降低(P<0.05),且GSH-PX、SOD升高(P<0.05);肺间质及肺泡水肿和岀血较少,仅见少量中性粒细胞浸润,且W/D明显较低(P<0.05)。结论:电针足三里可以通过抑制氧化应激反应来减少单肺通气引起的肺损伤。
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| 关 键 词： | 单肺通气 氧化应激 电针 足三里 |
Effect of Electroacupuncture of Zusanli(ST 36) on Oxidative Stress Rseponse by One Lung Ventilation |
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| REN Qiu-sheng,CHEN Xue-qin,WANG Jun-lu,BAO Feng-feng,JIANG liu-ming. Effect of Electroacupuncture of Zusanli(ST 36) on Oxidative Stress Rseponse by One Lung Ventilation[J]. Chinese Archives of Traditional Chinese Medicine, 2011, 0(12): 2738-2740 |
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| Authors: | REN Qiu-sheng CHEN Xue-qin WANG Jun-lu BAO Feng-feng JIANG liu-ming |
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| Affiliation: | REN Qiu-sheng1,CHEN Xue-qin1,WANG Jun-lu2,BAO Feng-feng1,JIANG liu-ming2(1.Yinzhou People's Hospital,Ningbo 315040,Zhejiang,China,2.First Affiliated Hospital of Wenzhou Medical College,Wenzhou 325000,china) |
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| Abstract: | Objective:To observe the effects of electroacupuncture of Zusanli(ST 36) on oxidative stress rseponse and lung injury degree during one lung ventilation.Methods:39 healthy New Zealand rabbits were randomized into three groups(n=13):electroacupuncture at no point group(EN),electroacupuncture at Zusanli points(EP)and control group(C).Tracheostomy was performed following with anesthesia,and endotracheal tube was inserted.Two lungs were ventilated for 30 min,followed by single right lung ventilation for 3 h,by ... |
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| Keywords: | One lung ventilation Oxidative stress Electroacupuncture Zusanli(ST 36) |
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